How to Build CHD@ZJU

CHD related Articles were retrieved from Pubmed, by entering keywords "coronary heart disease" and constrict the publish date from 2000/1/1 to now (2013/1/23). As a result, totally 115898 articles were found and their abstracts were downloaded for text mining. Since some articles didn't contain abstracts, only 88396 abstracts remained.

The text-mining process to get CHD related genes could be divided in to 5 following steps:

  • 1) Extracting all keywords from abstracts and ignoring those keywords start with numbers. 101402 keywords were extracted.

  • 2) Input these keywords into Gene library in ArrayTrack and find possible related genes. 4674 genes were then found.

  • 3) Put these 4674 genes again into pubmed abstracts to find related aticles. Only genes which offical name or there keyword description (such as prolactin for gene PRL) could be found in the abstract would be remained. As a result, 1247 genes were remained.

  • 4) Manually examined on the 1247 genes to validate it was acutally related to CHD. Some genes would be filtered if it represents other meanings (such as gene CAD, Entrez ID:790, carbamoyl-phosphate synthetase 2, is mostly meant coronary arterial disease in articles). 681 genes were then validated with at least one reference.

  • 5) All genes was compared with 1078 CHD genes in RGD database, and 370 genes were overlapped. These 370 genes were labels as "RGD_Supported" and the other 293 genes were labels as "REFERED". All 663 genes had supported references in CHD@ZJU which were examined by step 4.
  • How To contact Us

    Collaboration Information: Prof. Xiaohui Fan (fanxh@zju.edu.cn)

    Website using assistance : Leihong Wu (11019004@zju.edu.cn)



    Basic Information

    Gene Name: CETP

    Description: "cholesteryl ester transfer protein, plasma"

    Entrez Gene ID: 1071

    SwissProt Acc Number: P11597

    RefSeq: NM_000078

    It was suspected to be CHD related:

    ..Plasma cholesteryl ester transfer protein (CETP) promotes the cholesterol enrichment of apoB-containing lipoproteins (VLDL and LDL) at the expense of HDL. ..

    From PMID: 22474067, in Journal J Lipid Res , 2012


    References

    There were 168 potential papers with CETP and CHD.

    PMIDTitleJournalsDetails
    23962777 "HDL cholesterol in cardiovascular diseases: the good, the bad, and the ugly?"International journal of cardiologyMore Details
    24188894 "Evaluation of Lipids, Drug Concentration, and Safety Parameters Following Cessation of Treatment With the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Patients With or at High Risk for Coronary Heart Disease."The American journal of cardiologyMore Details
    24034746 "Cholesteryl ester transfer protein inhibitors in coronary heart disease: Validated comparative QSAR modeling of N, N-disubstituted trifluoro-3-amino-2-propanols."Computers in biology and medicineMore Details
    24078569 [Influence of CETP gene -629C/A polymorphism on the efficacy of atorvastatin treatment and clinical outcome].Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = ChineseMore Details
    24283500 CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population.Lipids in health and diseaseMore Details
    24280342 Activation of paraoxonase 1 is associated with HDL remodeling ex vivo.Clinica chimica acta; international journal of clinical chemistryMore Details
    23891427 Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis.The American journal of cardiologyMore Details
    23505323 Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.Journal of medical geneticsMore Details
    23042613 Structural features of cholesteryl ester transfer protein: a molecular dynamics simulation study.ProteinsMore Details
    23652567 Effects of cholesteryl ester transfer protein inhibitors on human lipoprotein metabolism: why have they failed in lowering coronary heart disease risk?Current opinion in lipidologyMore Details
    23666884 Diagnosis and management of familial dyslipoproteinemias.Current cardiology reportsMore Details
    23129316 "Apo A5 -1131T/C, FgB -455G/A, -148C/T, and CETP TaqIB gene polymorphisms and coronary artery disease in the Chinese population: a meta-analysis of 15,055 subjects."Molecular biology reportsMore Details
    23941686 An update on the discovery and development of cholesteryl transfer protein inhibitors for reducing residual cardiovascular risk.Journal of medicinal chemistryMore Details
    23567794 Systematic Review of CETP Inhibitors for Increasing High-Density Lipoprotein Cholesterol: Where Do These Agents Stand in the Approval Process?American journal of therapeuticsMore Details
    23269286 Inhibition of cholesteryl ester transfer protein by anacetrapib does not impair the anti-inflammatory properties of high density lipoprotein.Biochimica et biophysica actaMore Details
    23758630 Association of CETP Taq1B and -629C > A polymorphisms with coronary artery disease and lipid levels in the multi-ethnic Singaporean population.Lipids in health and diseaseMore Details
    22854712 Four polymorphisms of cholesteryl ester transfer protein gene and coronary stenosis in a Tunisian population."Journal of cardiovascular medicine (Hagerstown, Md.)"More Details
    22902152 Drugs targeting high-density lipoprotein cholesterol for coronary artery disease management.The Canadian journal of cardiologyMore Details
    23126252 Effects of dalcetrapib in patients with a recent acute coronary syndrome.The New England journal of medicineMore Details
    22556171 Association between TaqIB polymorphism of cholesteryl ester transfer protein and coronary artery disease in the Chinese population.Journal of Zhejiang University. Science. BMore Details
    21986251 The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype.Biochimica et biophysica actaMore Details
    21876547 Cholesterol efflux from macrophages is influenced differentially by plasmas from overweight insulin-sensitive and -resistant subjects.International journal of obesity (2005)More Details
    22474067 Constitutive inhibition of plasma CETP by apolipoprotein C1 is blunted in dyslipidemic patients with coronary artery disease.Journal of lipid researchMore Details
    22650305 Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors.Journal of medicinal chemistryMore Details
    22003152 Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.European heart journalMore Details
    21819519 "Efficacy and safety of dalcetrapib in type 2 diabetes mellitus and/or metabolic syndrome patients, at high cardiovascular disease risk.""Diabetes, obesity & metabolism"More Details
    22253581 Lipid exchange mechanism of the cholesteryl ester transfer protein clarified by atomistic and coarse-grained simulations.PLoS computational biologyMore Details
    22143414 "Genetic variation in cholesterol ester transfer protein, serum CETP activity, and coronary artery disease risk in Asian Indian diabetic cohort."Pharmacogenetics and genomicsMore Details
    23565387 High-density lipoprotein cholesterol: How High.Indian journal of endocrinology and metabolismMore Details
    22723175 HDL and CETP Inhibition: Will This DEFINE the Future?Current treatment options in cardiovascular medicineMore Details
    22345126 Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial.European heart journalMore Details
    22329439 Dalcetrapib--restoring belief in modulating CETP as a beneficial mechanism in cardiovascular disease.Expert opinion on investigational drugsMore Details
    23050023 Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.PloS oneMore Details
    23157875 Strong interaction between T allele of endothelial nitric oxide synthase with B1 allele of cholesteryl ester transfer protein TaqIB highly elevates the risk of coronary artery disease and type 2 diabetes mellitus.Human genomicsMore Details
    22661899 Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases.Vascular health and risk managementMore Details
    22403620 "Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk."PloS oneMore Details
    22623978 A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.PloS oneMore Details
    22952570 "Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol."PloS oneMore Details
    21908036 Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial.LancetMore Details
    21689002 Association between cholesteryl ester transfer protein TaqIB variants and risk of coronary artery disease and diabetes mellitus in the population of western Iran.Genetic testing and molecular biomarkersMore Details
    21961529 Investigational CETP antagonists for hyperlipidemia and atherosclerosis prevention.Expert opinion on investigational drugsMore Details
    21398511 siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids.Journal of lipid researchMore Details
    22229114 Common Variants in 6 Lipid-Related Genes Discovered by High-Resolution DNA Melting Analysis and Their Association with Plasma Lipids.Journal of clinical & experimental cardiologyMore Details
    21128879 Rationale and design of dal-VESSEL: a study to assess the safety and efficacy of dalcetrapib on endothelial function using brachial artery flow-mediated vasodilatation.Current medical research and opinionMore Details
    21909703 CETP Inhibition: does the future look promising?Current cardiology reportsMore Details
    21957197 "Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure."Journal of lipid researchMore Details
    22011848 Thrombospondin-4 polymorphism (A387P) predicts cardiovascular risk in postinfarction patients with high HDL cholesterol and C-reactive protein levels.Thrombosis and haemostasisMore Details
    21352420 Smaller low-density lipoprotein size as a possible risk factor for the prevalence of coronary artery diseases in haemodialysis patients: associations of cholesteryl ester transfer protein and the hepatic lipase gene polymorphism with low-density lipoprotein size."Nephrology (Carlton, Vic.)"More Details
    21252261 Association of anti-oxidized LDL and candidate genes with severity of coronary stenosis in the Women's Ischemia Syndrome Evaluation study.Journal of lipid researchMore Details
    21899732 The role of common variants of the cholesteryl ester transfer protein gene in left main coronary artery disease.Lipids in health and diseaseMore Details
    20599873 High density lipoprotein-anionic peptide factor effect on reverse cholesterol transport in type 2 diabetic patients with and without coronary artery disease.Clinical biochemistryMore Details
    20799898 Cholesteryl ester transfer protein Taq1B polymorphism in an angiographically assessed Turkish population: no effects on coronary artery disease risk.Genetic testing and molecular biomarkersMore Details
    20578904 "Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy."DNA and cell biologyMore Details
    19815603 Lack of association between the cholesteryl ester transfer protein gene--TaqIB polymorphism and coronary restenosis following percutaneous transluminal coronary angioplasty and stenting: a pilot study.AngiologyMore Details
    22460205 "Genetic variants at the APOE, lipoprotein lipase (LpL), cholesteryl ester transfer protein (CETP), and endothelial nitric oxide (eNOS) genes and coronary artery disease (CAD): CETP Taq1 B2B2 associates with lower risk of CAD in Asian Indians."Journal of community geneticsMore Details
    20434407 Update on genetics of postprandial lipemia.Atherosclerosis. SupplementsMore Details
    20497463 Cholesteryl ester transfer protein in patients with coronary heart disease.European journal of clinical investigationMore Details
    20065167 Cholesteryl ester transfer protein and mortality in patients undergoing coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study.CirculationMore Details
    19876761 Protective modulation of carotid atherosclerosis in hyperalphalipoproteinemic individuals.The international journal of cardiovascular imagingMore Details
    20097702 Safety and tolerability of dalcetrapib (RO4607381/JTT-705): results from a 48-week trial.European heart journalMore Details
    20082258 [HDL and CETP in atherogenesis].Deutsche medizinische Wochenschrift (1946)More Details
    20855565 Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.Journal of lipid researchMore Details
    20691300 On-statin cholesteryl ester transfer protein mass and risk of recurrent coronary events (from the pravastatin or atorvastatin evaluation and infection therapy-thrombolysis in myocardial infarction 22 [PROVE IT-TIMI 22] study).The American journal of cardiologyMore Details
    20398902 Common cholesteryl ester transfer protein gene variation related to high-density lipoprotein cholesterol is not associated with decreased coronary heart disease risk after a 10-year follow-up in a Mediterranean cohort: Modulation by alcohol consumption.AtherosclerosisMore Details
    20489166 Cholesteryl ester transfer protein polymorphism (TaqIB) associates with risk in postinfarction patients with high C-reactive protein and high-density lipoprotein cholesterol levels."Arteriosclerosis, thrombosis, and vascular biology"More Details
    20842556 High-density lipoprotein therapy: is there hope?Current treatment options in cardiovascular medicineMore Details
    20653333 Anacetrapib."American journal of cardiovascular drugs : drugs, devices, and other"More Details
    20200605 Cholesteryl ester transfer protein gene polymorphisms and longevity syndrome.The open cardiovascular medicine journalMore Details
    19558216 A combination of proatherogenic single-nucleotide polymorphisms is associated with increased risk of coronary artery disease and myocardial infarction in Asian Indians.DNA and cell biologyMore Details
    19781408 Design of the DEFINE trial: determining the EFficacy and tolerability of CETP INhibition with AnacEtrapib.American heart journalMore Details
    19784962 Association of cholesteryl ester transfer protein -629C > A polymorphism with high-density lipoprotein cholesterol levels in coronary artery disease patients.Cell biochemistry and functionMore Details
    19895939 Lessons learned from the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events (ILLUMINATE) trial.The American journal of cardiologyMore Details
    19457483 Where are we with probucol: a new life for an old drug?AtherosclerosisMore Details
    19397474 Antiproteinuric therapy decreases LDL-cholesterol as well as HDL-cholesterol in non-diabetic proteinuric patients: relationships with cholesteryl ester transfer protein mass and adiponectin.Expert opinion on therapeutic targetsMore Details
    18823627 "Association of lipoprotein lipase D9N polymorphism with myocardial infarction in type 2 diabetes: the genetics, outcomes, and lipids in type 2 diabetes (GOLD) study."AtherosclerosisMore Details
    19336475 Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.Human molecular geneticsMore Details
    19015220 High-density lipoprotein: why all the fuss?Annals of clinical biochemistryMore Details
    19948972 Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community.CirculationMore Details
    19958854 Rationale and design of the dal-OUTCOMES trial: efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome.American heart journalMore Details
    19810818 Combined hepatic lipase -514C/T and cholesteryl ester transfer protein I405V polymorphisms are associated with the risk of coronary artery disease.Genetic testing and molecular biomarkersMore Details
    19168039 "Cholesteryl ester transfer protein TaqIB, -629C>A and I405V polymorphisms and risk of coronary heart disease in an Indian population."Clinica chimica acta; international journal of clinical chemistryMore Details
    19023137 The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis.Journal of lipid researchMore Details
    19728844 TaqIB polymorphism in cholesterol ester transfer protein (CETP) gene predicts future cardiovascular death in patients experiencing an acute coronary syndrome.Clinical chemistry and laboratory medicine : CCLM / FESCCMore Details
    19878569 Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.BMC medical geneticsMore Details
    19085339 Is high HDL cholesterol always good?Annals of medicineMore Details
    19691831 "Gene polymorphisms in APOE, NOS3, and LIPC genes may be risk factors for cardiac adverse events after primary CABG."Journal of cardiothoracic surgeryMore Details
    18485135 Viability of developing CETP inhibitors.Cardiovascular therapeuticsMore Details
    18164013 High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants.AtherosclerosisMore Details
    19056069 Association of the cholesteryl ester transfer protein Taq1 B2B2 genotype with higher high-density lipoprotein cholesterol concentrations and lower risk of coronary artery disease in a Tunisian population.Archives of cardiovascular diseasesMore Details
    18243217 "Cholesteryl ester transfer protein genetic polymorphisms, HDL cholesterol, and subclinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis."AtherosclerosisMore Details
    18957472 CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction.European heart journalMore Details
    18637884 Cholesteryl ester transfer protein (CETP) genetic variation and early onset of non-fatal myocardial infarction.Annals of human geneticsMore Details
    18503096 Cholesteryl ester transfer protein activity and cardiovascular events in patients with chronic kidney disease stage V."Nephrology, dialysis, transplantation : official publication of the European"More Details
    19103817 Targeting residual cardiovascular risk: raising high-density lipoprotein cholesterol levels.Postgraduate medical journalMore Details
    18414186 HDL metabolism and CETP inhibition.Cardiology in reviewMore Details
    18560005 "Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk."JAMA : the journal of the American Medical AssociationMore Details
    18480348 Targeting residual cardiovascular risk: raising high-density lipoprotein cholesterol levels.Heart (British Cardiac Society)More Details
    18289550 "Synergistic effects of the apolipoprotein E epsilon3/epsilon2/epsilon4, the cholesteryl ester transfer protein TaqIB, and the apolipoprotein C3 -482 C>T polymorphisms on their association with coronary artery disease."AtherosclerosisMore Details
    18063597 "Alcohol consumption, TaqIB polymorphism of cholesteryl ester transfer protein, high-density lipoprotein cholesterol, and risk of coronary heart disease in men and women."European heart journalMore Details
    18193043 Newly identified loci that influence lipid concentrations and risk of coronary artery disease.Nature geneticsMore Details
    19029466 "Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation)."CirculationMore Details
    18787507 Pharmacological effects of lipid-lowering drugs recapitulate with a larger amplitude the phenotypic effects of common variants within their target genes.Pharmacogenetics and genomicsMore Details
    18783479 Reduced leucocyte cholesteryl ester transfer protein expression in acute coronary syndromes.Journal of internal medicineMore Details
    18230960 Optimal management of combined dyslipidemia: what have we behind statins monotherapy?Advances in cardiologyMore Details
    17604633 2D Quantitative structure-activity relationship studies on a series of cholesteryl ester transfer protein inhibitors.Bioorganic & medicinal chemistryMore Details
    17403027 The use of meta-analysis risk estimates for candidate genes in combination to predict coronary heart disease risk.Annals of human geneticsMore Details
    17984165 Effects of torcetrapib in patients at high risk for coronary events.The New England journal of medicineMore Details
    17666459 The CETP TaqIB polymorphism is associated with the risk of sudden death in type 2 diabetic patients.Diabetes careMore Details
    17512363 Multiple less common genetic variants explain the association of the cholesteryl ester transfer protein gene with coronary artery disease.Journal of the American College of CardiologyMore Details
    17287950 "Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease."Human geneticsMore Details
    17387129 Effect of torcetrapib on the progression of coronary atherosclerosis.The New England journal of medicineMore Details
    17433279 "Circulating small dense LDL, endothelial injuring factors and fibronectin in healthy postmenopausal women."Clinica chimica acta; international journal of clinical chemistryMore Details
    17512305 Cholesteryl ester transfer protein B1B1 genotype as a predictor of coronary artery disease in Taiwanese with type 2 diabetes mellitus.Metabolism: clinical and experimentalMore Details
    16890925 Common variants of Cholesteryl ester transfer protein gene and their association with lipid parameters in healthy volunteers of Tamilian population.Clinica chimica acta; international journal of clinical chemistryMore Details
    17121756 Inhibition of CETP as a novel therapeutic strategy for reducing the risk of atherosclerotic disease.European heart journalMore Details
    18047853 Refocusing on use of cholesteryl ester transfer protein inhibitors.The American journal of cardiologyMore Details
    18047849 "Increasing high-density lipoprotein cholesterol, inhibition of cholesteryl ester transfer protein, and heart disease risk reduction."The American journal of cardiologyMore Details
    17337099 [New insights and perspectives in the management of dyslipidemia].La Revue de medecine interne / fondee ... par la Societe nationale francaise deMore Details
    17275808 Cholesteryl ester transfer protein gene polymorphisms are associated with coronary artery disease in Corsican population (France).Experimental and molecular pathologyMore Details
    17310124 Cholesteryl ester-transfer protein (CETP) polymorphism and the association of acute coronary syndromes by obesity status in Greek subjects: the CARDIO2000-GENE study.Human heredityMore Details
    16684835 An increased coronary risk is paradoxically associated with common cholesteryl ester transfer protein gene variations that relate to higher high-density lipoprotein cholesterol: a population-based study.The Journal of clinical endocrinology and metabolismMore Details
    16574234 Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease.Pharmacology & therapeuticsMore Details
    17046334 Vaccines for the prevention of cardiovascular disease.Vascular pharmacologyMore Details
    16822236 CETP (cholesteryl ester transfer protein) promoter -1337 C>T polymorphism protects against coronary atherosclerosis in Japanese patients with heterozygous familial hypercholesterolaemia."Clinical science (London, England : 1979)"More Details
    16759183 High-resolution characterization of linkage disequilibrium structure and selection of tagging single nucleotide polymorphisms: application to the cholesteryl ester transfer protein gene.Annals of human geneticsMore Details
    15899484 Genotype of the mutant LDL receptor allele is associated with LDL particle size heterogeneity in familial hypercholesterolemia.AtherosclerosisMore Details
    16458126 Targeting cholesteryl ester transfer protein for the prevention and management of cardiovascular disease.Journal of the American College of CardiologyMore Details
    16433590 Inhibitors of cholesteryl ester transfer protein--a new approach to coronary artery disease.Expert opinion on investigational drugsMore Details
    16359930 "Pharmacogenetics: progress, pitfalls and clinical potential for coronary heart disease."Vascular pharmacologyMore Details
    16855848 The two novel CETP mutations Gln87X and Gln165X in a compound heterozygous state are associated with marked hyperalphalipoproteinemia and absence of significant coronary artery disease."Journal of molecular medicine (Berlin, Germany)"More Details
    16882279 Plasma cholesteryl ester transfer protein concentrations predict cardiovascular events in patients with coronary artery disease treated with pravastatin.Journal of internal medicineMore Details
    16763159 Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants."Arteriosclerosis, thrombosis, and vascular biology"More Details
    16832162 "Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction."Current opinion in lipidologyMore Details
    16049032 "Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study."Human molecular geneticsMore Details
    16098387 Carriers of three polymorphisms of cholesteryl ester transfer protein gene are at increased risk to coronary heart disease in a Chinese population.International journal of cardiologyMore Details
    15882786 Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease.Neuroscience lettersMore Details
    15386541 Effects of cholesterol ester transfer protein Taq1B gene polymorphism on serum lipoprotein levels in Turkish coronary artery disease patients.Cell biochemistry and functionMore Details
    15655129 "Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects."CirculationMore Details
    15550473 Increased plasma lipid-poor apolipoprotein A-I in patients with coronary artery disease.Clinical chemistryMore Details
    15585212 "Effects of increasing doses of simvastatin on fasting lipoprotein subfractions, and the effect of high-dose simvastatin on postprandial chylomicron remnant clearance in normotriglyceridemic patients with premature coronary sclerosis."AtherosclerosisMore Details
    15585206 Relationship between gene polymorphisms and prevalence of myocardial infarction among diabetic and non-diabetic subjects.AtherosclerosisMore Details
    15694928 Lipid transfer proteins (LTP) and atherosclerosis.AtherosclerosisMore Details
    16248996 Prevalence of genetic risk factors for coronary artery disease in Corsica island (France).Experimental and molecular pathologyMore Details
    16086925 Candidate gene susceptibility variants predict intermediate end points but not angiographic coronary artery disease.American heart journalMore Details
    16039291 Cholesterol ester transfer protein (CETP) Taq1B polymorphism influences the effect of a standardized cardiac rehabilitation program on lipid risk markers.AtherosclerosisMore Details
    15766738 Association of plasma cholesteryl ester transfer protein activity and polymorphism with coronary artery disease extent in Tunisian type II diabetic patients.Clinical biochemistryMore Details
    15337694 Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study.CirculationMore Details
    15461565 Raising high-density lipoprotein cholesterol with inhibitors of cholesteryl ester transfer protein - a new approach to coronary artery disease.Expert opinion on investigational drugsMore Details
    15342674 A review of CETP and its relation to atherosclerosis.Journal of lipid researchMore Details
    15488860 Analysis of gender-specific atherosclerosis susceptibility in transgenic[hCETP]25DS rat model.AtherosclerosisMore Details
    14967821 A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly.Journal of lipid researchMore Details
    14998629 The cholesteryl ester transfer protein (CETP) TaqIB polymorphism in the cholesterol and recurrent events study: no interaction with the response to pravastatin therapy and no effects on cardiovascular outcome: a prospective analysis of the CETP TaqIB polymorphism on cardiovascular outcome and interaction with cholesterol-lowering therapy.Journal of the American College of CardiologyMore Details
    15080555 "Phage-displayed recombinant single-chain antibody fragments with high affinity for cholesteryl ester transfer protein (CETP): cDNA cloning, characterization and CETP quantification."Clinical chemistry and laboratory medicine : CCLM / FESCCMore Details
    15026427 Relationship between cholesteryl ester transfer protein and LDL heterogeneity in familial hypercholesterolemia.Journal of lipid researchMore Details
    15071125 Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol.The New England journal of medicineMore Details
    15085362 [Genetic variation of the cholesterol ester transfer protein gene and the prevalence of coronary artery disease. The AtheroGene case control study].Zeitschrift fur KardiologieMore Details
    14531818 Hepatic lipase mutation may reduce vascular disease prevalence in hemodialysis patients with high CETP levels.Kidney internationalMore Details
    12647264 Cholesteryl ester transfer protein and lecithin:cholesterol acyltransferase activities in hispanic and anglo postmenopausal women: associations with total and regional body fat.Metabolism: clinical and experimentalMore Details
    12840658 Genetics of HDL regulation in humans.Current opinion in lipidologyMore Details
    14660992 The cholesteryl ester transfer protein Taq1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease.American heart journalMore Details
    12476935 Gene polymorphism and coronary risk factors in Indian population.Clinical chemistry and laboratory medicine : CCLM / FESCCMore Details
    12174215 Genetic and environmental determinants of plasma high density lipoprotein cholesterol and apolipoprotein AI concentrations in healthy middle-aged men.Annals of human geneticsMore Details
    11772294 Novel agents for managing dyslipidaemia.Expert opinion on investigational drugsMore Details
    11398152 Lipoprotein profile and cholesteryl ester transfer protein in neonates.Metabolism: clinical and experimentalMore Details
    11431184 Cholesteryl ester transfer protein as a protective factor against vascular disease in hemodialysis patients.American journal of kidney diseases : the official journal of the National KidneyMore Details
    11140626 Genetic polymorphisms and activity of cholesterol ester transfer protein (CETP): should we be measuring them?Clinical chemistry and laboratory medicine : CCLM / FESCCMore Details
    10861897 Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction.Genetic epidemiologyMore Details
    10754410 HDL cholesterol and TaqIB cholesteryl ester transfer protein gene polymorphism in renal transplant recipients.NephronMore Details

    NOTEs: These result is mostly from TEXT-MINING and there might have mismatches.



    PPI interactions

    There were totally 5 unique genes interacted with CETP. Show PPI network

    Gene nameInteraction typereference PMIDCHD relation
    EWSR1 Two-hybrid16189514|16189514 No
    CETP in vitro3818596 CHD related
    ARPC3 yeast 2-hybrid16169070 No
    LPL in vivo9374130 CHD related
    APOA1 in vivo9305883 CHD related


    Involved FDA drugs

    There was no drug associated with CETP