How to Build CHD@ZJU

CHD related Articles were retrieved from Pubmed, by entering keywords "coronary heart disease" and constrict the publish date from 2000/1/1 to now (2013/1/23). As a result, totally 115898 articles were found and their abstracts were downloaded for text mining. Since some articles didn't contain abstracts, only 88396 abstracts remained.

The text-mining process to get CHD related genes could be divided in to 5 following steps:

  • 1) Extracting all keywords from abstracts and ignoring those keywords start with numbers. 101402 keywords were extracted.

  • 2) Input these keywords into Gene library in ArrayTrack and find possible related genes. 4674 genes were then found.

  • 3) Put these 4674 genes again into pubmed abstracts to find related aticles. Only genes which offical name or there keyword description (such as prolactin for gene PRL) could be found in the abstract would be remained. As a result, 1247 genes were remained.

  • 4) Manually examined on the 1247 genes to validate it was acutally related to CHD. Some genes would be filtered if it represents other meanings (such as gene CAD, Entrez ID:790, carbamoyl-phosphate synthetase 2, is mostly meant coronary arterial disease in articles). 681 genes were then validated with at least one reference.

  • 5) All genes was compared with 1078 CHD genes in RGD database, and 370 genes were overlapped. These 370 genes were labels as "RGD_Supported" and the other 293 genes were labels as "REFERED". All 663 genes had supported references in CHD@ZJU which were examined by step 4.
  • How To contact Us

    Collaboration Information: Prof. Xiaohui Fan (

    Website using assistance : Leihong Wu (

    Basic Information

    Gene Name: CIMT

    Description: Carotid intimal medial thickness

    Entrez Gene ID: 404677

    SwissProt Acc Number:


    It was supported literatures to be a novel CHD related gene:

    ..Periodontal disease with elevated bacterial exposure is associated with CHD events and early atherogenesis (CIMT)..

    From PMID: 18052701, in Journal J Periodontol. , 2007


    There were 197 potential papers with CIMT and CHD.

    24019084 Endothelial and Platelet Function in Children With Previous Kawasaki Disease.AngiologyMore Details
    24135385 Low Prevalence of Sublinical Atherosclerosis in Asymptomatic Patients With Type 1 Diabetes Mellitus in a European Mediterranean Population.Diabetes careMore Details
    24075754 A systematic review: burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; should we care?AtherosclerosisMore Details
    24219389 Evaluation of Carotid Intima-Media Thickness and Aortic Elasticity in Patients with Nondipper Hypertension."Echocardiography (Mount Kisco, N.Y.)"More Details
    24268528 "Carotid intima-media thickness is increased in patients with treated mucopolysaccharidosis types I and II, and correlates with arterial stiffness."Molecular genetics and metabolismMore Details
    23852762 Cardiovascular risk stratification in rheumatic diseases: carotid ultrasound is more sensitive than Coronary Artery Calcification Score to detect subclinical atherosclerosis in patients with rheumatoid arthritis.Annals of the rheumatic diseasesMore Details
    23647891 Comparison of diagnostic utilities of ankle-brachial index and Carotid intima-media thickness as surrogate markers of significant coronary atherosclerosis in Indians.Indian heart journalMore Details
    23505241 Carotid ultrasound is useful for the cardiovascular risk stratification of patients with rheumatoid arthritis: results of a population-based study.Annals of the rheumatic diseasesMore Details
    23347959 Differences in absolute risk of cardiovascular events using risk-refinement tests: a systematic analysis of four cardiovascular risk equations.AtherosclerosisMore Details
    23816777 Carotid intima-media thickness testing as an asymptomatic cardiovascular disease identifier and method for making therapeutic decisions.Postgraduate medicineMore Details
    23003220 Prevalence and extent of subclinical atherosclerosis in patients with psoriasis.Journal of internal medicineMore Details
    23611290 Association of automated carotid IMT measurement and HbA1c in Japanese patients with coronary artery disease.Diabetes research and clinical practiceMore Details
    23587283 Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study.AtherosclerosisMore Details
    23905108 The carotid intima media thickness: a predictor of the clincal coronary events.Journal of clinical and diagnostic research : JCDRMore Details
    23609339 Sonographic evaluation for predicting the presence and severity of coronary artery disease.Ultrasound quarterlyMore Details
    22192294 Carotid plaque is associated with increased cardiac mortality in patients with coronary artery disease.International journal of cardiologyMore Details
    23347332 "A novel echocardiographic method for the detection of subclinical atherosclerosis in newly diagnosed, untreated type 2 diabetes.""Echocardiography (Mount Kisco, N.Y.)"More Details
    23664201 Measures of cardiovascular risk and subclinical atherosclerosis in a cohort of women with a remote history of preeclampsia.AtherosclerosisMore Details
    22584246 Increased carotid and brachial intima-media thickness is related to diffuse coronary involvement rather than focal lesions.AngiologyMore Details
    23359783 Carotid Intima Media Thickness and its Association With Total Bilirubin Levels in Patients With Coronary Artery Ectasia.AngiologyMore Details
    23188791 Genetic polymorphisms associated with carotid artery intima-media thickness and coronary artery calcification in women of the Kronos Early Estrogen Prevention Study.Physiological genomicsMore Details
    22323838 Carotid intima-media thickness and carotid plaques improves prediction of obstructive angiographic coronary artery disease in women.AngiologyMore Details
    23580803 "Neutrophil-to-lymphocyte ratio, insulin resistance, and endothelial dysfunction in patients with autosomal dominant polycystic kidney disease."Indian journal of nephrologyMore Details
    23260320 Risk factors for stroke among patients with hypertension: a case-control study.Journal of the neurological sciencesMore Details
    23400346 Aortic valve sclerosis is a high predictive marker of systemic endothelial dysfunction in hypertensive patients.HerzMore Details
    23275344 Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.Circulation. Cardiovascular geneticsMore Details
    22899452 Silent cardiovascular involvement in patients with diffuse systemic sclerosis: a controlled cross-sectional study.Arthritis care & researchMore Details
    23799555 Serum fetuin-A levels are associated with carotid intima media thickness in patients with normotensive chronic obstructive pulmonary disease.Cardiology journalMore Details
    24178767 The link between vascular deterioration and branched chain amino acids in a population with high glycated haemoglobin: the SABPA study.Amino acidsMore Details
    23925993 Carotid intima-media thickness in children with Kawasaki disease.Rheumatology internationalMore Details
    23965231 SCORE and REGICOR function charts underestimate the cardiovascular risk in Spanish patients with rheumatoid arthritis.Arthritis research & therapyMore Details
    24217304 Increased carotid intima-media thickness associated with high hs-CRP levels is a predictor of unstable coronary artery disease.Cardiovascular journal of AfricaMore Details
    23665987 Can single cIMT measurement during echocardiography affect further investigation decision for coronary artery disease?Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiologyMore Details
    23179052 [Distribution of carotid intima media thickness in men and women with and without coronary heart disease. Cross-sectional data of the Heinz Nixdorf Recall Study].HerzMore Details
    23889858 Associations of retrospective and concurrent lipid levels with subclinical atherosclerosis prediction after 20 years of follow-up: the Coronary Artery Risk Development in Young Adults (CARDIA) study.Annals of epidemiologyMore Details
    23613039 Carotid Intima-Media Thickness in Patients With Slow Coronary Flow and Its Association With Neutrophil-to-Lymphocyte Ratio: A Preliminary Report.Clinical and applied thrombosis/hemostasis : official journal of theMore Details
    23908858 Viewpoint: personalizing statin therapy.Rambam Maimonides medical journalMore Details
    23442989 Long-term health benefits and costs of measurement of carotid intima-media thickness in prevention of coronary heart disease.Journal of hypertensionMore Details
    23312232 "Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS)."Fertility and sterilityMore Details
    24066233 Patients with Obstructive Sleep Apnea Display Increased Carotid Intima Media: A Meta-Analysis.International journal of vascular medicineMore Details
    24098074 Carotid intima-media thickness and plaque occurrence in predicting stable angiographic coronary artery disease.Clinical interventions in agingMore Details
    23641873 Particulate matter components and subclinical atherosclerosis: common approaches to estimating exposure in a Multi-Ethnic Study of Atherosclerosis cross-sectional study.Environmental health : a global access science sourceMore Details
    24143102 Detection of subclinical atherosclerosis and diastolic dysfunction in patients with schizophrenia.Neuropsychiatric disease and treatmentMore Details
    23349927 "Psychological factors, including alexithymia, in the prediction of cardiovascular risk in HIV infected patients: results of a cohort study."PloS oneMore Details
    23360132 "Vascular calcification on plain radiographs is associated with carotid intima media thickness, malnutrition and cardiovascular events in dialysis patients: a prospective observational study."BMC nephrologyMore Details
    23874496 Association of mitochondrial genetic variation with carotid atherosclerosis.PloS oneMore Details
    24286297 The ZC3HC1 rs11556924 polymorphism is associated with increased carotid intima-media thickness in patients with rheumatoid arthritis.Arthritis research & therapyMore Details
    23967275 Silent ischemic heart disease and pericardial fat volume in HIV-infected patients: a case-control myocardial perfusion scintigraphy study.PloS oneMore Details
    22816732 High-dose statin therapy does not induce insulin resistance in patients with familial hypercholesterolemia.Metabolic syndrome and related disordersMore Details
    22519624 Subclinical endothelial dysfunction and low-grade inflammation play roles in the development of erectile dysfunction in young men with low risk of coronary heart disease.International journal of andrologyMore Details
    22795336 Association of glycated hemoglobin with carotid intimal medial thickness in Asian Indians with normal glucose tolerance.Journal of diabetes and its complicationsMore Details
    22935396 Short sleep duration is associated with carotid intima-media thickness among men in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.Stroke; a journal of cerebral circulationMore Details
    22377394 Characteristics of earlier atherosclerotic involvement in adolescent patients with Kawasaki disease and coronary artery lesions: significance of gray scale median on B-mode ultrasound.AtherosclerosisMore Details
    22154316 "Age modification of the association of lipoprotein, lipid, and lipoprotein ratio with carotid intima-media thickness (from the Multi-Ethnic Study of Atherosclerosis [MESA])."The American journal of cardiologyMore Details
    22265271 High-resolution radial artery intima-media thickness and cardiovascular risk factors in patients with suspected coronary artery disease--comparison with common carotid artery intima-media thickness.AtherosclerosisMore Details
    22378036 "Effect of 1-year anti-TNF-alpha therapy on aortic stiffness, carotid atherosclerosis, and calprotectin in inflammatory arthropathies: a controlled study."American journal of hypertensionMore Details
    22503547 Evaluation of possible subclinical atherosclerosis in adolescents with a family history of premature atherosclerosis.AtherosclerosisMore Details
    22460051 Detection of subclinical atherosclerosis in familial hypercholesterolemia using non-invasive imaging modalities.AtherosclerosisMore Details
    22127628 The relationship between mechanical properties of carotid artery and coronary artery disease.European heart journal cardiovascular ImagingMore Details
    23129906 Endothelial dysfunction and atherosclerosis in children with irreversible pulmonary hypertension due to congenital heart disease.Annals of pediatric cardiologyMore Details
    22789936 Carotid plaque burden as a measure of subclinical atherosclerosis: comparison with other tests for subclinical arterial disease in the High Risk Plaque BioImage study.JACC. Cardiovascular imagingMore Details
    21948972 Increased carotid intima-media thickness is associated with higher SYNTAX score.AngiologyMore Details
    21666250 Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study.European heart journalMore Details
    21764060 "Carotid plaque, compared with carotid intima-media thickness, more accurately predicts coronary artery disease events: a meta-analysis."AtherosclerosisMore Details
    21118411 Insulin resistance and coronary flow velocity reserve in patients with autosomal dominant polycystic kidney disease.Internal medicine journalMore Details
    22095617 Improvements in risk stratification for the occurrence of cardiovascular disease by imaging subclinical atherosclerosis: a systematic review.Heart (British Cardiac Society)More Details
    22214742 "Association between C-reactive protein, carotid intima-media thickness and P-wave dispersion in obese premenopausal women: an observational study."Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiologyMore Details
    22564353 Paradoxical progression of atherosclerosis related to low-density lipoprotein reduction and exposure to ezetimibe.European heart journalMore Details
    23152477 Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk.Circulation. Cardiovascular geneticsMore Details
    22850442 Low-dose rosuvastatin improves the functional and morphological markers of atherosclerosis in asymptomatic postmenopausal women with dyslipidemia."Menopause (New York, N.Y.)"More Details
    22827403 Association of serum amyloid A with subclinical atherosclerosis in women with gestational diabetes.Gynecological endocrinology : the official journal of the International SocietyMore Details
    22796256 "High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (multi-ethnic study of atherosclerosis)."Journal of the American College of CardiologyMore Details
    21697209 Common carotid intima-media thickness in cardiovascular risk stratification of older people: the Rotterdam Study.European journal of preventive cardiologyMore Details
    22749515 Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study.AtherosclerosisMore Details
    22622962 "Study design, rationale, and baseline characteristics: evaluation of fenofibric acid on carotid intima-media thickness in patients with type IIb dyslipidemia with residual risk in addition to atorvastatin therapy (FIRST) trial."Cardiovascular drugs and therapy / sponsored by the International Society ofMore Details
    22007031 Serum uric acid: a marker of metabolic syndrome and subclinical atherosclerosis in Korean men.AngiologyMore Details
    22863158 Can metabolic syndrome presence predict carotid intima-media thickness?"Journal of clinical hypertension (Greenwich, Conn.)"More Details
    22281656 The role of carotid intimal thickness and plaque imaging in risk stratification for coronary heart disease.Current atherosclerosis reportsMore Details
    22321873 Maximum carotid intima-media thickness improves the prediction ability of coronary artery stenosis in type 2 diabetic patients without history of coronary artery disease.AtherosclerosisMore Details
    22621394 Evaluation of the future atherosclerotic heart disease with oxidative stress and carotid artery intima media thickness in gestational diabetes mellitus.Endocrine researchMore Details
    23107930 "Carotid plaque, carotid intima-media thickness, and coronary calcification equally discriminate prevalent cardiovascular disease in kidney disease."American journal of nephrologyMore Details
    22295058 "Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies."PloS oneMore Details
    23133318 Vascular effects of bisphosphonates-a systematic review.Clinical medicine insights. Endocrinology and diabetesMore Details
    22606325 Type I interferons are associated with subclinical markers of cardiovascular disease in a cohort of systemic lupus erythematosus patients.PloS oneMore Details
    23259073 Cardiac autonomic neuropathy measured by heart rate variability and markers of subclinical atherosclerosis in early type 2 diabetes.ISRN endocrinologyMore Details
    22272073 Indicators of the atherogenic lipoprotein phenotype measured with density gradient ultracentrifugation predict changes in carotid intima-media thickness in men and women.Vascular health and risk managementMore Details
    23056349 Mutation C3256T of mitochondrial genome in white blood cells: novel genetic marker of atherosclerosis and coronary heart disease.PloS oneMore Details
    21788202 Evaluation of the effects of chronic biomass fuel smoke exposure on peripheral endothelial functions: an observational study.Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiologyMore Details
    21909108 Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.Nature geneticsMore Details
    21785969 MESA: the NIH-sponsored study that validates atherosclerosis imaging for primary prevention.Current atherosclerosis reportsMore Details
    21817101 Association of atherosclerosis with expression of the LILRB1 receptor by human NK and T-cells supports the infectious burden hypothesis."Arteriosclerosis, thrombosis, and vascular biology"More Details
    21844289 Impact of subclinical atherosclerosis on cardiovascular disease events in individuals with metabolic syndrome and diabetes: the multi-ethnic study of atherosclerosis.Diabetes careMore Details
    21792639 "The role of atherosclerosis imaging in redefining normal and abnormal cholesterol values, and risk reduction in primary prevention statin trials."Current atherosclerosis reportsMore Details
    21814753 Ultrasound imaging of carotid intima-media thickness: an office-based tool to assist physicians in cardiovascular risk assessment.Current atherosclerosis reportsMore Details
    22115642 The associations of fetuin-A with subclinical cardiovascular disease in community-dwelling persons: the Rancho Bernardo Study.Journal of the American College of CardiologyMore Details
    21918474 "Algorithms to measure carotid intima-media thickness in trials: a comparison of reproducibility, rate of progression and treatment effect."Journal of hypertensionMore Details
    21854440 The predictive value of flow-mediated dilation and carotid artery intima-media thickness for occult coronary artery disease."Echocardiography (Mount Kisco, N.Y.)"More Details
    21600518 Predictors of anterior and posterior wall carotid intima media thickness progression in men and women at moderate risk of coronary heart disease.Journal of clinical lipidologyMore Details
    21080031 High fibrinogen level is an independent predictor of presence and extent of coronary artery disease among Italian population.Journal of thrombosis and thrombolysisMore Details
    21414468 Investigating air pollution and atherosclerosis in humans: concepts and outlook.Progress in cardiovascular diseasesMore Details
    22783281 Glycemic and blood pressure control in older patients with hypertension and diabetes: association with carotid atherosclerosis.Journal of geriatric cardiology : JGCMore Details
    21474823 "Association between obesity, high-sensitivity C-reactive protein >/=2 mg/L, and subclinical atherosclerosis: implications of JUPITER from the Multi-Ethnic Study of Atherosclerosis.""Arteriosclerosis, thrombosis, and vascular biology"More Details
    21610270 Effect of rimonabant on carotid intima-media thickness (CIMT) progression in patients with abdominal obesity and metabolic syndrome: the AUDITOR Trial.Heart (British Cardiac Society)More Details
    21701401 "Firefighters, heart disease, and aspects of insulin resistance: the FEMA Firefighter Heart Disease Prevention study."Journal of occupational and environmental medicine / American College ofMore Details
    21276382 Carotid intima-media thickness correlation with lipid profile in patients with familial hypercholesterolemia versus controls.Journal of the College of Physicians and Surgeons--Pakistan : JCPSPMore Details
    21110214 Amino-terminal pro-brain natriuretic peptide as a prognostic marker in patients with rheumatoid arthritis.Clinical rheumatologyMore Details
    21112055 Appropriate use criteria for carotid intima media thickness testing.AtherosclerosisMore Details
    21035803 Abdominal aortic calcium and multi-site atherosclerosis: the Multiethnic Study of Atherosclerosis.AtherosclerosisMore Details
    21270201 Relationship between carotid intima-media thickness and the presence and extent of coronary stenosis in type 2 diabetic patients with carotid atherosclerosis but without history of coronary artery disease.Diabetes careMore Details
    21786187 Alterations in platelet function and cell-derived microvesicles in recently menopausal women: relationship to metabolic syndrome and atherogenic risk.Journal of cardiovascular translational researchMore Details
    22247905 "Cardiovascular Risk Assessment with Vascular Function, Carotid Atherosclerosis and the UKPDS Risk Engine in Korean Patients with Newly Diagnosed Type 2 Diabetes."Diabetes & metabolism journalMore Details
    21647752 The correlation of serum trace elements and heavy metals with carotid artery atherosclerosis in maintenance hemodialysis patients.Biological trace element researchMore Details
    21999752 Effect of 2-year treatment with low-dose rosuvastatin on intima-media thickness in hypercholesterolemic subjects with asymptomatic carotid artery disease.Expert opinion on pharmacotherapyMore Details
    20930713 Associations of SNPs in ADIPOQ and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis (MESA)."Obesity (Silver Spring, Md.)"More Details
    21792295 "Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey.""Drug design, development and therapy"More Details
    21535886 Heart-type fatty acid binding protein (H-FABP): relationship with arterial intima-media thickness and role as diagnostic marker for atherosclerosis in patients with impaired glucose metabolism.Cardiovascular diabetologyMore Details
    22161434 Cardiac testing for coronary artery disease in potential kidney transplant recipients.The Cochrane database of systematic reviewsMore Details
    21812947 "NT-proBNP levels, atherosclerosis and vascular function in asymptomatic type 2 diabetic patients with microalbuminuria: peripheral reactive hyperaemia index but not NT-proBNP is an independent predictor of coronary atherosclerosis."Cardiovascular diabetologyMore Details
    20626666 A comparison of assessment of coronary calcium vs carotid intima media thickness for determination of vascular age and adjustment of the Framingham Risk Score.Preventive cardiologyMore Details
    20846602 Association of combinations of lipid parameters with carotid intima-media thickness and coronary artery calcium in the MESA (Multi-Ethnic Study of Atherosclerosis).Journal of the American College of CardiologyMore Details
    19782983 Relationship between common carotid intima-media thickness and thoracic aortic calcification: the Multi-Ethnic Study of Atherosclerosis.AtherosclerosisMore Details
    20486958 The relation between the color M-mode propagation velocity of the descending aorta and coronary and carotid atherosclerosis and flow-mediated dilatation."Echocardiography (Mount Kisco, N.Y.)"More Details
    19762025 The role of carotid intima-media thickness assessment in cardiovascular risk evaluation in patients with polyvascular atherosclerosis.AtherosclerosisMore Details
    20025644 Longitudinal assessment of fibrinogen in relation to subclinical cardiovascular disease: the CARDIA study.Journal of thrombosis and haemostasis : JTHMore Details
    20399059 "The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration."Journal of the American College of CardiologyMore Details
    20138620 Longitudinal association between toenail selenium levels and measures of subclinical atherosclerosis: the CARDIA trace element study.AtherosclerosisMore Details
    21122625 Carotid intima-media thickness for the practicing lipidologist.Journal of clinical lipidologyMore Details
    20117440 A high ankle brachial index is associated with greater left ventricular mass MESA (Multi-Ethnic Study of Atherosclerosis).Journal of the American College of CardiologyMore Details
    19951938 Structural and functional vascular alterations and incident hypertension in normotensive adults: the Multi-Ethnic Study of Atherosclerosis.American journal of epidemiologyMore Details
    19876761 Protective modulation of carotid atherosclerosis in hyperalphalipoproteinemic individuals.The international journal of cardiovascular imagingMore Details
    19657788 Endothelial function and cardiovascular risk stratification in menopausal women.Climacteric : the journal of the International Menopause SocietyMore Details
    19918012 Increased carotid intima-media thickness as a predictor of the presence and extent of abnormal myocardial perfusion in type 2 diabetes.Diabetes careMore Details
    19948842 The value of carotid intima-media thickness for predicting cardiovascular risk."Arteriosclerosis, thrombosis, and vascular biology"More Details
    20522535 "A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients."Clinical journal of the American Society of Nephrology : CJASNMore Details
    20554155 High prevalence of ultrasound detected carotid atherosclerosis in subjects with low Framingham risk score: potential implications for screening for subclinical atherosclerosis.Journal of the American Society of Echocardiography : official publication of theMore Details
    20591621 Carotid ultrasound identifies high risk subclinical atherosclerosis in adults with low framingham risk scores.Journal of the American Society of Echocardiography : official publication of theMore Details
    20378078 Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study.Journal of the American College of CardiologyMore Details
    19476580 Factors associated with low levels of subclinical vascular disease in older adults: multi-ethnic study of atherosclerosis.Preventive cardiologyMore Details
    19549732 The association between A1C and subclinical cardiovascular disease: the multi-ethnic study of atherosclerosis.Diabetes careMore Details
    19801021 Usefulness of carotid intima-media thickness in patients with diabetes mellitus as a predictor of coronary artery disease.The American journal of cardiologyMore Details
    19766760 Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk for coronary heart disease.The American journal of cardiologyMore Details
    19801303 Manual B-mode versus automated radio-frequency carotid intima-media thickness measurements.Journal of the American Society of Echocardiography : official publication of theMore Details
    19892054 Screening for subclinical coronary artery disease measuring carotid intima media thickness.The American journal of cardiologyMore Details
    19500958 Cerebrovascular disease in diabetes mellitus: the role of carotid intima-media thickness."Nutrition, metabolism, and cardiovascular diseases : NMCD"More Details
    19632982 "HIV positivity, protease inhibitor exposure and subclinical atherosclerosis: a systematic review and meta-analysis of observational studies."Heart (British Cardiac Society)More Details
    19406278 Clinical and research applications of carotid intima-media thickness.The American journal of cardiologyMore Details
    18849030 Sex hormone levels and subclinical atherosclerosis in postmenopausal women: the Multi-Ethnic Study of Atherosclerosis.AtherosclerosisMore Details
    19293413 ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial.JAMA : the journal of the American Medical AssociationMore Details
    18675980 Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes.AtherosclerosisMore Details
    19252109 Carotid intima-media thickness and coronary artery calcium score as indications of subclinical atherosclerosis.Mayo Clinic proceedings. Mayo ClinicMore Details
    19148561 Serum 25-hydroxyvitamin d levels are not associated with subclinical vascular disease or C-reactive protein in the old order amish.Calcified tissue internationalMore Details
    19520251 Risk factors associated with aortic and carotid intima-media thickness in adolescents and young adults: the Muscatine Offspring Study.Journal of the American College of CardiologyMore Details
    19949610 Carotid intima-media thickness and pulse wave velocity after recovery from kawasaki disease.Korean circulation journalMore Details
    18602107 Elevated fibrinogen levels and subsequent subclinical atherosclerosis: the CARDIA Study.AtherosclerosisMore Details
    19482299 Risk factor treatment in veteran women at risk for cardiovascular disease.The Journal of surgical researchMore Details
    19949637 Prevalence and significance of carotid plaques in patients with coronary atherosclerosis.Korean circulation journalMore Details
    19446849 The type of LDLR gene mutation predicts cardiovascular risk in children with familial hypercholesterolemia.The Journal of pediatricsMore Details
    18836986 Subclinical atherosclerosis is weakly associated with lower cognitive function in healthy hyperhomocysteinemic adults without clinical cardiovascular disease.International journal of geriatric psychiatryMore Details
    19115078 Relationship between carotid artery intima-media thickness and brachial artery flow-mediated dilation in peritoneal dialysis patients.International urology and nephrologyMore Details
    20043836 Relationship between carotid intima-media thickness and coronary angiographic findings: a prospective study.Cardiovascular ultrasoundMore Details
    18599798 Coronary artery disease-associated locus on chromosome 9p21 and early markers of atherosclerosis."Arteriosclerosis, thrombosis, and vascular biology"More Details
    18810577 Carotid intima-media thickness in pre- and postmenopausal women with suspected coronary artery disease.Heart and vesselsMore Details
    18262532 Carotid artery intima-media thickness correlates with intravascular ultrasound parameters in patients with slow coronary flow.AtherosclerosisMore Details
    18805900 "The association of coronary artery calcification and carotid artery intima-media thickness with distinct, traditional coronary artery disease risk factors in asymptomatic adults."American journal of epidemiologyMore Details
    19037584 Association of breast arterial calcification and carotid intima-media thickness.Heart and vesselsMore Details
    18194137 Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study."Clinical science (London, England : 1979)"More Details
    18292760 Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.American journal of hypertensionMore Details
    18418233 Subclinic atherosclerosis and cardiovascular risk factors in HIV-infected children: PERI study.Coronary artery diseaseMore Details
    17727858 Progression of calcified coronary atherosclerosis: relationship to coronary risk factors and carotid intima-media thickness.AtherosclerosisMore Details
    17803999 Brachial artery vasoreactivity is associated with cross-sectional and longitudinal anatomical measures of atherosclerosis in postmenopausal women with coronary artery disease.AtherosclerosisMore Details
    17320091 Carotid atherosclerosis and vascular age in the assessment of coronary heart disease risk beyond the Framingham Risk Score.AtherosclerosisMore Details
    18093595 Phosphorus levels are associated with subclinical atherosclerosis in the general population.AtherosclerosisMore Details
    18359319 Usefulness of increased skin cholesterol to identify individuals at increased cardiovascular risk (from the Predictor of Advanced Subclinical Atherosclerosis study).The American journal of cardiologyMore Details
    18369358 Pulse pressure amplification and risk of cardiovascular disease.American journal of hypertensionMore Details
    18334471 Ultrasound imaging techniques for the evaluation of cardiovascular therapies.European heart journalMore Details
    17903688 Carotid intima-media thickness as a marker of cardiovascular risk in hypertensive patients with coronary artery disease.American journal of hypertensionMore Details
    17478140 Usefulness of carotid ultrasound to improve the ability of stress testing to predict coronary artery disease.The American journal of cardiologyMore Details
    17443100 "Carotid intima-media thickness, carotid distensibility and mitral, aortic valve calcification: a useful diagnostic parameter of systemic atherosclerotic disease.""Journal of cardiovascular medicine (Hagerstown, Md.)"More Details
    17384434 Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial.JAMA : the journal of the American Medical AssociationMore Details
    17355745 Carotid intima-media thickness in low-risk individuals with asymptomatic atherosclerosis: baseline data from the METEOR study.Current medical research and opinionMore Details
    17052775 Effect of folic acid treatment on carotid intima-media thickness of patients with coronary disease.International journal of cardiologyMore Details
    17584566 Peroxisome proliferator-activated receptor gamma agonists for the Prevention of Adverse events following percutaneous coronary Revascularization--results of the PPAR study.American heart journalMore Details
    17277033 Carotid intima-media thickness and coronary atherosclerosis: weak or strong relations?European heart journalMore Details
    17113061 Do mutations causing low HDL-C promote increased carotid intima-media thickness?Clinica chimica acta; international journal of clinical chemistryMore Details
    18052701 Markers of systemic bacterial exposure in periodontal disease and cardiovascular disease risk: a systematic review and meta-analysis.Journal of periodontologyMore Details
    18004111 Associations of isoprostanes-related oxidative stress with surrogate subclinical indices and angiographic measures of atherosclerosis.Coronary artery diseaseMore Details
    16945751 Clinical value of carotid intima-media thickness testing.Journal of nuclear cardiology : official publication of the American Society ofMore Details
    16388808 Hemoglobin and atherosclerosis in patients with manifest arterial disease. The SMART-study.AtherosclerosisMore Details
    17076979 Carotid intima-media thickness as a surrogate marker for cardiovascular disease in intervention studies.Current medical research and opinionMore Details
    16168418 Non-invasively measured structural and functional arterial characteristics and coronary heart disease risk in middle aged and elderly men.AtherosclerosisMore Details
    16000343 Carotid intima-media thickness: an index for subclinical atherosclerosis in type 1 diabetes.Journal of tropical pediatricsMore Details
    16305824 Noninvasive arterial measurements of vascular damage in healthy young adults: relation to coronary heart disease risk.Annals of epidemiologyMore Details
    15692111 A genome-wide scan for carotid artery intima-media thickness: the Mexican-American Coronary Artery Disease family study.Stroke; a journal of cerebral circulationMore Details
    16282542 Plasma adiponectin levels and sonographic phenotypes of subclinical carotid artery atherosclerosis: data from the SAPHIR Study.Stroke; a journal of cerebral circulationMore Details
    15301899 Atherosclerotic disease regression with statins: studies using vascular markers.International journal of cardiologyMore Details
    15537681 "Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins."CirculationMore Details
    12912713 Cardiovascular risk factors and increased carotid intima-media thickness in healthy young adults: the Atherosclerosis Risk in Young Adults (ARYA) Study.Archives of internal medicineMore Details

    NOTEs: These result is mostly from TEXT-MINING and there might have mismatches.

    PPI interactions

    There was NO PPI interaction information about CIMT

    Involved FDA drugs

    There was no drug associated with CIMT