How to Build CHD@ZJU

CHD related Articles were retrieved from Pubmed, by entering keywords "coronary heart disease" and constrict the publish date from 2000/1/1 to now (2013/1/23). As a result, totally 115898 articles were found and their abstracts were downloaded for text mining. Since some articles didn't contain abstracts, only 88396 abstracts remained.
The text-mining process to get CHD related genes could be divided in to 5 following steps:

  • 1) Extracting all keywords from abstracts and ignoring those keywords start with numbers. 101402 keywords were extracted.

    •
  • 2) Input these keywords into Gene library in ArrayTrack and find possible related genes. 4674 genes were then found.

  • 3) Put these 4674 genes again into pubmed abstracts to find related aticles. Only genes which offical name or there keyword description (such as prolactin for gene PRL) could be found in the abstract would be remained. As a result, 1247 genes were remained.

    •
  • 4) Manually examined on the 1247 genes to validate it was acutally related to CHD. Some genes would be filtered if it represents other meanings (such as gene CAD, Entrez ID:790, carbamoyl-phosphate synthetase 2, is mostly meant coronary arterial disease in articles). 681 genes were then validated with at least one reference.

  • 5) All genes was compared with 1078 CHD genes in RGD database, and 370 genes were overlapped. These 370 genes were labels as "RGD_Supported" and the other 293 genes were labels as "REFERED". All 663 genes had supported references in CHD@ZJU which were examined by step 4.

    • How To contact Us

    Collaboration Information: Prof. Xiaohui Fan (fanxh@zju.edu.cn)

    Website using assistance : Leihong Wu (11019004@zju.edu.cn)



    Basic Information

    Gene Name: HDAC1

    Description: histone deacetylase 1

    This suspected gene is newly curated in the Version 2.0

    It was suspected to be CHD related:

    ..the predominant effect of HDAC inhibition, mainly mediated by class I HDACs, is to prevent cardiac hypertrophy in response to a broad range of agonist and stretch stimuli...

    From PMID: 16380549, in Journal Circulation. 2006;113:51-59 ,


    References

    There were 0 potential papers with HDAC1 and CHD.

    NOTEs: These result is mostly from TEXT-MINING and there might have mismatches.



    PPI interactions

    There were totally 491 unique genes interacted with HDAC1. Show PPI network

    Gene nameInteraction typereference PMIDCHD relation
    KDM1A Co-purification12032298|11171972|11102443|11102443|17634443|20585571|20856864|22318606|21670149 No
    HMG20B Affinity Capture-Western12032298 No
    HDAC2 Co-purification12032298|12920132|12920132|11804585|11466315|11739383|11564889|10444591|9520398|9150135|10581039|19041848|11919195|11919195|15987735|11102443|15297431|18059533|9790534|9790534|9885572|9885572|22416134|22318606|21670149|22939629 CHD related
    CTBP1 Reconstituted Complex11022042|10995736 No
    TGIF1 Affinity Capture-Western10995736|11427533|11226163|11226163,18511908 No
    DDX5 Affinity Capture-Western15298701 No
    DDX17 Affinity Capture-Western15298701 No
    SIN3A Affinity Capture-Western12943729|12920132|12920132|10220385|11931768|11171972|10444591|12091390|9520398|12374985|10640275|11784859|14593184|14647463|16331260|15695521|11602581|11118440|11102443|9790534|9790534|17643391|20585571|9885572 No
    MTA1 Affinity Capture-MS12920132|11146623|14722073|20585571|9885572|9885572|21670149|22939629 No
    MTA2 Affinity Capture-MS12920132|11171972|10444591|12374985|19686092|11602581|11102443|11102443|9790534|20585571|20127688|21670149|22939629 No
    HDAC1 Affinity Capture-MS12920132|10898795,14645126,15138260 CHD related
    CHD4 Affinity Capture-MS12920132|12920132|10220385|9804427|11102443|9790534|9790534|9790534|20585571|9885572|9885572|21670149 No
    RBBP7 Affinity Capture-Western12920132|10471499|10444591|9150135|19686092|11102443|9790534|9790534|9885572|22939629 No
    CHD1 Affinity Capture-Western12890497 No
    YY1 Reconstituted Complex9346952|11940654|22318606 No
    GTF2I Affinity Capture-Western12393887 No
    HSPD1 Affinity Capture-Western11777905 CHD related
    HSPA4 Affinity Capture-Western11777905 No
    TOP2B Affinity Capture-Western11062478|11062478|11136718 No
    TOP2A Affinity Capture-Western11062478|11136718|11136718|11136718 No
    NCOR2 Affinity Capture-Western11739383|22318606|11739383 No
    PML Reconstituted Complex11430826|11430826|11259576|11259576|11259576|18644863|11430826,11259576 No
    MYOD1 Reconstituted Complex11684023|11285237,11684023 No
    NFKB1 Affinity Capture-Western11931769|11931769|12972430|16319923|11931769,14678988 CHD related
    MDM2 Affinity Capture-Western12426395|15640443|22318606|12426395 CHD related
    Foxg1 Affinity Capture-Western11238932 No
    RBL1 Affinity Capture-Western10490602|9724731 No
    FKBP3 Affinity Capture-Western11532945|11532945 No
    PPARD Affinity Capture-Western11867749|11867749 CHD related
    MIER1 Affinity Capture-Western12482978 No
    TGIF2 Affinity Capture-Western11427533 No
    DAXX Far Western10669754|10669754 No
    SIN3B Co-purification10444591|15935060|11102443|20585571|11959842 No
    HBP1 Affinity Capture-Western15235594 No
    IKZF1 Affinity Capture-Western10357820|12015313 No
    CHD3 Affinity Capture-Western9804427|11784859|20585571|9885572|9885572 No
    BCL6 Affinity Capture-Western9627120|15454082|9753732|22318606 No
    CABIN1 Affinity Capture-Western10933397 No
    VHL Reconstituted Complex11641274|22286234 No
    HIF1AN Reconstituted Complex11641274 No
    HIF1A Reconstituted Complex11641274|17273746|17273746|22318606|21148070 CHD related
    HUS1 Two-hybrid10846170|10846170 No
    RAD9A Affinity Capture-Western10846170 No
    ING1 Affinity Capture-Western12015309|18193082|11118440 No
    RUNX1T1 Affinity Capture-Western11533236|17389244 No
    CBX5 Affinity Capture-Western12242305 No
    HR Affinity Capture-Western11641275 No
    DZIP3 Affinity Capture-Western18206970 No
    SPI1 Affinity Capture-Western14647463|16331260|11593411 No
    WHSC1 Affinity Capture-Western16197452|18156491 No
    ZMYND11 Affinity Capture-Western16565076 No
    ETHE1 Affinity Capture-Western17353187 No
    REST Reconstituted Complex18806873 No
    PRDM1 Affinity Capture-Western19124609 No
    FRA10F Affinity Capture-Western20154723 No
    GLI2 Affinity Capture-Western20081843 No
    CDK5R1 Affinity Capture-Western19081376 No
    SMARCA4 Affinity Capture-Western19081374|20596014 No
    PPP1CC Affinity Capture-Western19070599|12567184 No
    HSF1 Affinity Capture-Western19793920 CHD related
    POU2F1 Affinity Capture-Western19617623|19617623 No
    SMAD7 Affinity Capture-Western15831498|15831498|15831516 No
    HELLS Co-localization19561196|19561196|17967891 No
    PPA1 Affinity Capture-Western17008050 No
    NKX2-5 Affinity Capture-Western18851995 CHD related
    BRMS1 Affinity Capture-Western17000776 No
    SERPINB5 Affinity Capture-Western16982778|16982778 No
    UBC Affinity Capture-Western15640443 No
    CNTN2 Affinity Capture-Western16865259|12370815|12370815 No
    PAX3 Affinity Capture-Western16787918 No
    CREBBP Affinity Capture-Western16787918|16528103 No
    GATAD2A Reconstituted Complex16738318|22939629 No
    NKX3-1 Affinity Capture-Western16697957 No
    RUNX1 Affinity Capture-Western16652147|21059642 CHD related
    NUP98 Reconstituted Complex16651408|16651408 No
    NUP54 Affinity Capture-Western16651408 No
    MAPK8 Affinity Capture-Western16611996 CHD related
    MAPK9 Affinity Capture-Western16611996 CHD related
    MAPK10 Affinity Capture-Western16611996 No
    TRIM27 Co-localization19351825 No
    NKX3-2 Reconstituted Complex14612411 No
    ESR1 Affinity Capture-Western14506733|14506733|15557281|14722073|17312152 CHD related
    CRYAB Affinity Capture-Western18552382 No
    ESCO2 Affinity Capture-Western18501190 No
    CIITA Reconstituted Complex12697811 CHD related
    HES1 Affinity Capture-Western16195230 No
    GLI3 Affinity Capture-Western12435627 No
    HSD11B2 Affinity Capture-Western12082639 CHD related
    MYT1 Affinity Capture-Western15935060 No
    CCND1 Affinity Capture-Western15713663 CHD related
    NKX2-2 Affinity Capture-Western15695521 No
    NFKBIA Affinity Capture-Western15536134|12972430 CHD related
    MYC Affinity Capture-Western18271930|18003922|22286234 CHD related
    TBP Affinity Capture-Western11313951 No
    TP73 Affinity Capture-Western15454570|15454570 No
    UHRF2 Affinity Capture-Western15361834 No
    ACTA1 Affinity Capture-MS11102443 CHD related
    PBX1 Affinity Capture-Western11046157 No
    SENP1 Affinity Capture-Western15199155|15199155 No
    TAF1B Affinity Capture-Western15136563 No
    UBASH3B Affinity Capture-MS9790534 No
    BHLHE41 Reconstituted Complex17487425 No
    NONO Co-localization17452459 No
    ZNF148 Affinity Capture-Western17663720 No
    PRDM5 Affinity Capture-Western17636019 No
    SAMSN1 Affinity Capture-Western20478393 No
    SMC4 Affinity Capture-MS20585571 No
    CCT8 Affinity Capture-MS20585571 No
    TCP1 Affinity Capture-MS20585571 No
    VIM Affinity Capture-MS20585571 CHD related
    TRIM21 Affinity Capture-MS20585571 No
    UL28 Affinity Capture-MS20585571 No
    UL29 Affinity Capture-MS20585571 No
    UL38 Affinity Capture-MS20585571|20585571 No
    ESCO1 Affinity Capture-Western20331966 No
    IRF5 Affinity Capture-Western20935208 No
    PPP6R3 Affinity Capture-MS9885572 No
    DBC1 Affinity Capture-Western21030595 No
    HIST3H3 Biochemical Activity12700765 No
    FOXP3 Affinity Capture-Western21974802 CHD related
    MAP1LC3B Synthetic Growth Defect22496786 No
    UBTF Co-localization22393235 No
    PLK4 Biochemical Activity22318606|22318606 No
    MCM6 Biochemical Activity22318606|22318606 No
    GMNN Biochemical Activity22318606|22318606 No
    CS Biochemical Activity22318606|22318606 No
    SET Biochemical Activity22318606|22318606 No
    RICTOR Biochemical Activity22318606|22318606 No
    RUVBL1 Biochemical Activity22318606|22318606 No
    PIK3R1 Biochemical Activity22318606|22318606 CHD related
    ABCG2 Negative Genetic22318606 CHD related
    ACACA Negative Genetic22318606 CHD related
    ANAPC5 Negative Genetic22318606 No
    ARNTL Negative Genetic22318606 No
    ASTL Negative Genetic22318606 No
    ATAD5 Negative Genetic22318606 No
    AURKA Negative Genetic22318606 No
    AURKAIP1 Negative Genetic22318606 No
    AURKB Negative Genetic22318606 No
    BCCIP Negative Genetic22318606 No
    BCL2L2 Negative Genetic22318606 No
    BCLAF1 Negative Genetic22318606 No
    BRCA2 Negative Genetic22318606 No
    CAMK2A Negative Genetic22318606 CHD related
    CDK2 Negative Genetic22318606 No
    CLOCK Negative Genetic22318606 No
    CORIN Negative Genetic22318606 No
    CSNK1D Negative Genetic22318606 No
    CSNK1E Negative Genetic22318606 No
    DYRK2 Negative Genetic22318606 No
    ELAVL1 Negative Genetic22318606 No
    EN1 Negative Genetic22318606 No
    HSP90AB1 Negative Genetic22318606 CHD related
    IGSF11 Negative Genetic22318606 No
    IKZF5 Negative Genetic22318606 No
    ING3 Negative Genetic22318606 No
    INO80D Negative Genetic22318606 No
    ITGB3BP Negative Genetic22318606 No
    KRAS Negative Genetic22318606 No
    KRT19 Negative Genetic22318606 No
    LGI4 Negative Genetic22318606 No
    LPHN2 Negative Genetic22318606 No
    MEF2B Negative Genetic22318606 No
    MFAP4 Negative Genetic22318606 No
    NAT8B Negative Genetic22318606 No
    NEFM Negative Genetic22318606 No
    NOS1 Negative Genetic22318606 CHD related
    NXF1 Negative Genetic22318606 No
    PCDH19 Negative Genetic22318606 No
    CDHR2 Negative Genetic22318606 No
    PDCD10 Negative Genetic22318606 No
    PDE8A Negative Genetic22318606 No
    PER1 Negative Genetic22318606 No
    PER2 Negative Genetic22318606 No
    PHKB Negative Genetic22318606 No
    PIAS1 Negative Genetic22318606 No
    PLK1 Negative Genetic22318606 No
    PLK2 Negative Genetic22318606 No
    PPARGC1B Negative Genetic22318606 No
    PRKAA2 Negative Genetic22318606 CHD related
    PRKAB1 Negative Genetic22318606 CHD related
    PRKAG1 Negative Genetic22318606 CHD related
    PRKAG2 Negative Genetic22318606 No
    PRKAR1A Negative Genetic22318606 CHD related
    RARB Negative Genetic22318606 No
    RASA2 Negative Genetic22318606 No
    RASL12 Negative Genetic22318606 No
    RXRA Negative Genetic22318606 CHD related
    SF3A1 Negative Genetic22318606 No
    SF3B1 Negative Genetic22318606 No
    SMURF1 Negative Genetic22318606 No
    SMYD3 Negative Genetic22318606 No
    STAT6 Negative Genetic22318606 CHD related
    SUMO1 Negative Genetic22318606 No
    TSC1 Negative Genetic22318606 No
    ULK1 Negative Genetic22318606 No
    ULK2 Negative Genetic22318606 No
    WNT1 Negative Genetic22318606 No
    XDH Negative Genetic22318606 CHD related
    YY1AP1 Negative Genetic22318606 No
    ACACB Positive Genetic22318606 No
    ACLY Positive Genetic22318606 No
    ALKBH7 Positive Genetic22318606 No
    HMGB3P1 Positive Genetic22318606 No
    KDM3A Positive Genetic22318606 No
    KLHL5 Positive Genetic22318606 No
    LECT2 Positive Genetic22318606 No
    MEAF6 Positive Genetic22318606 No
    KAT8 Positive Genetic22318606 No
    KAT6A Positive Genetic22318606 No
    PDK1 Positive Genetic22318606 No
    PIK3C3 Positive Genetic22318606 No
    PIK3R5 Positive Genetic22318606 No
    RAI1 Positive Genetic22318606 No
    RANGRF Positive Genetic22318606 No
    RARA Positive Genetic22318606 No
    CDKN2A Reconstituted Complex21846774|21846774 CHD related
    NR2C2 Affinity Capture-Western21670149 No
    POLD3 Affinity Capture-Western21670149 No
    TRIM28 Affinity Capture-Western21669397 No
    NFATC1 Affinity Capture-Western19218564 CHD related
    VprBP Reconstituted Complex22184063 No
    JDP2 Reconstituted Complex22989952 No
    ZNF76 Affinity Capture-Western16337145 No
    SMARCC1 Co-fractionation22939629 No
    SMARCA5 Co-fractionation22939629 No
    SMARCD1 Co-fractionation22939629 No
    ATRX in vivo14645126 No
    RUNX3 in vitro;in vivo15138260 No
    DDB2 in vitro8602529 No
    RFC4 in vitro12045192 No
    ZBTB16 Reconstituted Complex15467736|9627120|9627120|11865059|9627120,15467736 No
    MBD3L1 Affinity Capture-Western15456747 No
    BUB1 Affinity Capture-Western15388328|15388328 No
    BUB1B Affinity Capture-Western15388328|15388328 No
    BUB3 Affinity Capture-Western15388328|15388328|15388328 No
    CDC20 Affinity Capture-Western15388328|15388328 No
    CDH1 Affinity Capture-Western15388328|15388328 No
    MAD1L1 Affinity Capture-Western15388328|15388328 No
    RCOR1 Co-purification12032298|11171972|18806873|12192000|15897453|11102443 No
    PHF21A Co-purification12032298|15325272 No
    RB1 Affinity Capture-Western10779361|10615135|11684023|9491888|10490602|9724731|12473678|16766265|11583987|11158299|10958676|10778858|9988677|15044952|15003538|9468140|9468139|9468139|17827154|21900881|10499802 CHD related
    DNMT3B Co-purification15148359|15120635|15120635|12202768 No
    GATA1 Affinity Capture-Western14668799 No
    PHB Reconstituted Complex14637159|17932104 No
    CDYL Affinity Capture-Western12947414|12947414|19061646|12947414 No
    RBBP4 Affinity Capture-Western12943729|11470869|9150133|12091390|11602581|17827154|21670149|15451426,10734134,12943729,12091390,11302704 No
    SP1 Affinity Capture-Western12847090|11896613|12091390|12176973|19062177|18850004|16478997|12665570|12200149|16121030|16121030|16121030|15722551|15713621|15557281|15528196|11517158|15155736|18059533|17906119|20072153|21636851 No
    MLL Reconstituted Complex12829790|12829790 No
    TXNIP Affinity Capture-Western12821938|12821938 CHD related
    SAP30 Affinity Capture-Western12788099|9651585|9651585|10444591|15235594|11390640|11784859|16820529|11283269|9790534|9790534|15451426,9651585 No
    SAP130 Affinity Capture-Western12724404 No
    ARID4B Affinity Capture-Western12724404 No
    SUDS3 Affinity Capture-Western12724404|11909966|11909966 No
    HCFC1 Affinity Capture-MS12670868|12670868 No
    HINFP Affinity Capture-Western12665568 No
    PTMA Reconstituted Complex12634383 No
    EFCAB6 Affinity Capture-Western12612053 No
    AR Two-hybrid11994312|15640443|15835920 CHD related
    MBD3 Affinity Capture-Western12354758|10444591|12124384|19041848|16428440|17827154|12124384 No
    MBD2 Affinity Capture-Western12183469|10471499|10444591|11297506|17634443|10471499 No
    TAB2 Reconstituted Complex12150997 No
    GATAD2B Affinity Capture-Western11756549 No
    HDAC9 Affinity Capture-Western10655483|10487760|12590135 No
    RELA Affinity Capture-Western12419806|11931769|11931769|11564889|20001970|17000776|16483679|15192014|17827154|17962807 CHD related
    ATR Affinity Capture-Western10545197 No
    RFC1 Affinity Capture-Western12045192|12045192 No
    BRCA1 Reconstituted Complex10220405 CHD related
    Dnmt1 Reconstituted Complex10615135|10615135 No
    TP53 Affinity Capture-Western12426395|16107876|19011633|18765668|11313951|11099047|10777477|10521394|14976551|17827154|20633551|20075864|22266186|10777477,16959611 CHD related
    SMARCB1 Co-purification11238380 No
    SMARCA2 Co-purification11238380|12453419 No
    PCNA Affinity Capture-Western11929879|14988403 CHD related
    NFIX Affinity Capture-Western11896613 No
    RBL2 Affinity Capture-Western9724731|10969803 No
    E2F4 Affinity Capture-Western9724731 No
    BCOR Affinity Capture-Western10898795|10898795 No
    Nrip1 Reconstituted Complex11006275 No
    CBFA2T3 Affinity Capture-Western12242670|12242670 No
    E2F1 Affinity Capture-Western10734134 CHD related
    MECOM Affinity Capture-Western11552981|11552981 No
    KLF11 Reconstituted Complex11438660|11438660 No
    SMAD2 Affinity Capture-Western10199400|14699069|10199400 CHD related
    DNMT3L Reconstituted Complex12177302|12202768|12202768|12177302,12202768 No
    DNMT3A Reconstituted Complex11350943|11350943|19786833|11350943 No
    SATB1 Co-fractionation12374985|12374985|16630892|12374985 No
    PHF12 Affinity Capture-Western11390640|11390640 No
    SP3 Affinity Capture-Western12176973|12200149|11517158|17906119|12176973 No
    SUV39H1 Affinity Capture-Western11788710|11788710 No
    EED Affinity Capture-Western10581039|10581039|10581039 No
    EZH2 Affinity Capture-Western10581039|15520282|21685935|10581039 No
    TPD52L1 Two-hybrid16169070 No
    TAL1 Affinity Capture-MS16407974|19497860|19497860 No
    NR2F2 Reconstituted Complex10704340|10704340 No
    SPEN Affinity Capture-Western11331609|11331609 No
    TLE4 Affinity Capture-Western11266540 No
    HEY2 Reconstituted Complex11486045|11486045 CHD related
    IFRD1 Affinity Capture-Western12198164 No
    MXD1 Reconstituted Complex11101889 No
    UHRF1 Affinity Capture-Western17934516|19800870|15361834|22411829 No
    PADI4 Reconstituted Complex19581286|19581286|19581286 No
    MECP2 Affinity Capture-Western12473678 No
    MBD4 Two-hybrid15899845|15899845|15899845 No
    ING2 Affinity Capture-MS16387653|16387653|16728974 No
    H2AFY Affinity Capture-MS17158748|16107708|17474147 No
    KDM5C Affinity Capture-MS17468742 No
    ZMYM2 Affinity Capture-MS18806873 No
    CDKN1A Reconstituted Complex20154723|16082198 CHD related
    GLI1 Affinity Capture-Western20081843 No
    KCTD11 Affinity Capture-Western20081843 No
    APBB1 Affinity Capture-Western19343227 No
    BNIP3 Affinity Capture-Western19339613 CHD related
    SFPQ Affinity Capture-Western19339282|21106524|21566083|16731528 No
    ZBTB7A Affinity Capture-Western19244234 No
    MKX Affinity Capture-Western19235719 No
    CHFR Affinity Capture-Western19182791 No
    TLE1 Reconstituted Complex19101520|19101520 No
    DACH1 Affinity Capture-Western17182846 No
    NUDT21 Affinity Capture-Western17172643 No
    PAPOLA Affinity Capture-Western17172643 No
    BANF1 Affinity Capture-MS19759913 No
    ZFP36 Affinity Capture-Western19738286 No
    MBTPS1 Biochemical Activity19729656|19729656 No
    CEBPB Affinity Capture-Western19029947|21638299 No
    APPL1 Affinity Capture-Western19686092|19686092 CHD related
    BACH1 Affinity Capture-Western19011633 No
    ADD1 Affinity Capture-Western17074803 CHD related
    CREM Affinity Capture-Western17056544|17056544 CHD related
    JUN Affinity Capture-Western17056544 CHD related
    DACT1 Affinity Capture-Western18936100 No
    HOXA11 Affinity Capture-Western16963455 No
    FOSL1 Affinity Capture-Western15615716 No
    SAP30L Affinity Capture-Western16820529 No
    EP300 Affinity Capture-Western18722353|14968110 CHD related
    NR3C1 Affinity Capture-Western16762839 CHD related
    RUNX2 Affinity Capture-Western16728531|21972143|22393235 No
    RUVBL2 Affinity Capture-Western16699503|19433865|20603076|20603076 No
    tat Reconstituted Complex19454010 No
    GRIP1 Affinity Capture-Western16649994 No
    PLAGL1 Affinity Capture-Western18644983 No
    NFE4 Affinity Capture-Western15273251|15273251 No
    INSM1 Affinity Capture-Western16569215 No
    CEBPD Affinity Capture-Western18619497|17910034|17910034 No
    REPIN1 Affinity Capture-Western16540471|16540471 No
    GCM1 Affinity Capture-Western16528103|16528103 No
    RERE Affinity Capture-Western16481466 No
    Gug Affinity Capture-Western16481466 No
    RFX1 Affinity Capture-Western16464847 No
    SUMO2 Affinity Capture-MS19394292|21693764|19471022 No
    NFYC Affinity Capture-Western19351825 No
    SNAI1 Affinity Capture-Western14673164|20562920|21685935|23011797 No
    SNAI2 Affinity Capture-Western14673164|23011797 No
    SNAI3 Affinity Capture-Western14673164 No
    MEN1 Reconstituted Complex14559791 No
    BCL3 Affinity Capture-Western16306601|15469820|15469820 No
    LMO4 Affinity Capture-Western16288053 No
    SYK Affinity Capture-Western16288017|16288017 No
    GFI1 Affinity Capture-Western16287849 No
    CTNNB1 Affinity Capture-Western16204248|10958684|17412698 CHD related
    PARP1 Affinity Capture-Western16204234|16204234 CHD related
    E4F1 Affinity Capture-Western12730668|21666599 No
    MTA3 Affinity Capture-Western12705869|22075476 No
    BCL6B Two-hybrid12659862 No
    STAT5A Affinity Capture-Western12574125 No
    CREB1 Affinity Capture-Western12567184|20473547 No
    LCOR Reconstituted Complex12535528 No
    PITX2 Affinity Capture-Western12464179|12464179 No
    ALL1 Affinity Capture-Western12453419 No
    TAF6 Affinity Capture-Western12453419 No
    SMARCE1 Affinity Capture-Western12192000 No
    SMARCC2 Affinity Capture-Western12192000 No
    BCL11B Affinity Capture-Western16091750|16091750|17245431 No
    BCL11A Affinity Capture-Western16091750 No
    BAZ2A Reconstituted Complex16085498|12198165 No
    TFCP2 Reconstituted Complex11884454 No
    HIST1H3A Affinity Capture-MS11850410 No
    KDM4A Affinity Capture-Western15927959 No
    STAT3 Affinity Capture-Western15870198|15653507|22116549|22750444 CHD related
    NR0B2 Reconstituted Complex15835920|15835920|21262773|17895379|17895379 No
    CEBPA Affinity Capture-Western15713621 No
    MBD3L2 Reconstituted Complex15701600 No
    KLF5 Affinity Capture-Western15668237|15668237 CHD related
    CSNK2A1 Biochemical Activity11602581|11327722|17827154|11602581 CHD related
    PFDN5 Affinity Capture-Western11585818 No
    HNRNPD Affinity Capture-Western18413351|18413351 No
    NR2E1 Affinity Capture-MS18391013 No
    KLF4 Reconstituted Complex15561714 No
    KLF1 Reconstituted Complex15542849 No
    SATB2 Reconstituted Complex18333962 No
    MNT Affinity Capture-Western18271930 No
    TBX3 Affinity Capture-Western18245468 CHD related
    MAFK Affinity Capture-Western18241676 No
    PRKACA Biochemical Activity11327722|12082111 CHD related
    SMAD3 Two-hybrid11306568|10575014 CHD related
    ARID4A Affinity Capture-Western11283269 No
    ELK1 Reconstituted Complex11283259 No
    HDAC7 Reconstituted Complex11279209 No
    LEF1 Affinity Capture-Western10958684 No
    STRA13 Reconstituted Complex10737769 No
    ATM Reconstituted Complex10531300 No
    ENO1 Reconstituted Complex10403782|10403782 CHD related
    PHB2 Affinity Capture-Western15140878|15140878|15140878,15173318 No
    ZEB2 Affinity Capture-Western18182442 No
    SKIL Affinity Capture-Western10049357 No
    ZFPM2 Affinity Capture-MS18067919 No
    PIAS4 Reconstituted Complex14981544|12904571 No
    NR1D2 Reconstituted Complex9611234 No
    SOX6 Affinity Capture-Western17412698|17412698 No
    ZNF395 Reconstituted Complex17897615|17897615 No
    SMAD1 Affinity Capture-Western14699069 CHD related
    SMAD5 Affinity Capture-Western14699069 CHD related
    SMAD4 Affinity Capture-Western14699069 No
    SMEK1 Affinity Capture-Western21423269 No
    NPM1 Affinity Capture-Western17318229 No
    EMD Affinity Capture-MS17620012 No
    CCDC6 Affinity Capture-Western20498639|20498639|20498639 No
    OVOL1 Affinity Capture-Western17311813|17311813 No
    GABPA Affinity Capture-Western17304221 No
    MORF4L1 Affinity Capture-MS17573780|20332121 No
    MORF4L2 Affinity Capture-MS17573780|20332121 No
    DMAP1 Reconstituted Complex17371848|17371848 No
    DPF2 Affinity Capture-Western20400511 No
    ATF3 Affinity Capture-Western20360311 No
    PPARG Reconstituted Complex16407282 CHD related
    MEF2D Affinity Capture-Western20590529 No
    MEF2A Affinity Capture-Western20590529 CHD related
    PARK7 Affinity Capture-MS20127688|20127688 No
    TSC22D3 Affinity Capture-Western20124407 No
    CDK2AP1 Affinity Capture-Western20523938 No
    TADA2A Affinity Capture-MS20508642 No
    BANP Co-localization20075864 No
    NFYB Affinity Capture-Western20072153 No
    DEC1 Affinity Capture-Western20821348 No
    HIST2H2AA3 Affinity Capture-Western21179169 No
    DHX30 Affinity Capture-MS17255935|17255935|17255935 No
    NR2E3 Affinity Capture-Western17255935|17255935 No
    ARHGAP35 FRET21127047|21127047 No
    PPP2R1B Affinity Capture-Western17540176|17540176|17540176 No
    PPP2R1A Affinity Capture-Western17540176 No
    HDAC5 Affinity Capture-MS21081666 No
    KAT5 Affinity Capture-Western21045206|11994312 No
    HIST1H4A Reconstituted Complex14578449 No
    THAP11 Reconstituted Complex18585351 No
    PRKG1 Biochemical Activity12082111 CHD related
    NFYA Affinity Capture-Western21565167 No
    DDIT3 Affinity Capture-Western22242125 CHD related
    KIAA0101 Affinity Capture-MS21628590 No
    SMARCAD1 Affinity Capture-MS21549307|21549307 No
    SOX2 Affinity Capture-MS21532573 No
    KDM5B Affinity Capture-Western21502505|21937684|21937684|17373667 No
    HDGF Affinity Capture-MS21907836|21907836 No
    WISP2 Reconstituted Complex21262769 No
    PRDM4 Affinity Capture-Western15051733 No
    GPS2 Reconstituted Complex17895379|17895379 No
    NFKB2 Co-localization17962807 No
    RELB Co-localization17962807 No
    REL Co-localization17962807 No
    K8 Affinity Capture-Western22416134 No
    PCGF6 Affinity Capture-MS22325352 No
    RNF2 Affinity Capture-MS22325352 No
    PRKAA1 Synthetic Lethality22318606 CHD related
    HIST3H2BB Affinity Capture-MS21846774|21846774 No
    Dact2 Affinity Capture-Western21718540 No
    NR2C1 Affinity Capture-MS21670149|21670149 No
    tcf7l1a Affinity Capture-Western21666599 No
    lnx2b Affinity Capture-Western21666599 No
    KDM4C Affinity Capture-Western21637537 No
    TFAP4 Affinity Capture-MS19505873|19505873 No
    BAHD1 Affinity Capture-Western21252314|21252314 No
    Btg2 Reconstituted Complex17371797 No
    BMX Affinity Capture-Western15207703 No
    AIRE Affinity Capture-Western20185822 No
    BRMS1L Affinity Capture-MS15451426|15451426|15451426 No
    MAGEA1 Reconstituted Complex15316101|15316101 No
    APEX1 in vivo14633989 CHD related
    SALL1 in vivo11836251 No
    SAP18 in vitro;in vivo9150135 No
    HIC1 in vivo12052894 No
    SETDB1 in vitro;in vivo12398767 No
    RBP1 in vivo15451426 No
    HDAC3 in vitro10944117,11302704 CHD related
    UBE2I in vitro;in vivo11960997 No
    PIAS3 in vivo14691252 No
    MDS1 in vitro;in vivo11552981 No
    EID2 in vivo12586827 No
    CSNK2A2 in vitro11602581 No
    RBPJ in vitro;in vivo9694793 No
    RAP1A in vivo15207703 No
    STAT2 in vitro14645718 No
    PEX14 in vitro11863372 No
    EID2B in vitro;in vivo15970276 No


    Involved FDA drugs

    There was no drug associated with HDAC1