Collaboration Information: Prof. Xiaohui Fan (fanxh@zju.edu.cn)
Website using assistance : Leihong Wu (11019004@zju.edu.cn)
Coronary Heart Disease Research Platform
Description: histidine-rich glycoprotein
Entrez Gene ID: 3273
SwissProt Acc Number: P04196
RefSeq: NM_000412
It was suspected to be CHD related:
.."HRG may, therefore, play an important role in the development of coronary artery disease and the expansion of the atherosclerotic plaque and may locally regulate the expression of the angiogenetic factor CYR61."..
From PMID: 16155362, in Journal J Vasc Res , 2005There were 4 potential papers with HRG and CHD.
PMID | Title | Journals | Details |
---|---|---|---|
22703881 | "Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease." | American journal of human genetics | More Details |
17084425 | Predicting the impact of population level risk reduction in cardio-vascular disease and stroke on acute hospital admission rates over a 5 year period--a pilot study. | Public health | More Details |
16116047 | Cardiovascular morbidity and mortality in hypertensive patients with lower versus higher risk: a LIFE substudy. | Hypertension | More Details |
16155362 | Expression of heregulin in human coronary atherosclerotic lesions. | Journal of vascular research | More Details |
NOTEs: These result is mostly from TEXT-MINING and there might have mismatches.
There were totally 6 unique genes interacted with HRG. Show PPI network
Gene name | Interaction type | reference PMID | CHD relation |
---|---|---|---|
FGA | Reconstituted Complex | 9276466|9276466 | CHD related |
C1QA | in vivo | 9184145 | CHD related |
C1QB | in vivo | 9184145 | CHD related |
FCGR1A | in vivo | 10421785 | No |
PLG | in vivo | 8478593 | No |
THBS1 | in vivo | 6438154 | CHD related |
There was no drug associated with HRG