Basic Informations of Mineralocorticoid receptor

Entrez Gene ID: 110784 [Pubmed]

UniProt Protein Name: Mineralocorticoid receptor

UniProt ID: A3KN90

Related Drug:

DrugBank IDDrug Name
DB01134Desoxycorticosterone Pivalate
DB00588Fluticasone Propionate


PMID:21242479|Circulation. 2011;123:400-408
..."Moreover, cardiomyocyte-specific MR ablation prevented the increases in myocardial and mitochondrial O(2)(ยท-) production and upregulation of the NADPH oxidase subunits Nox2 and Nox4."...

PMID:18427128|Circulation. 2008;117:2253-2261
..."MR blockade reduced expression of proinflammatory and prothrombotic factors in adipose tissue and increased expression of adiponectin in heart and adipose tissue of obese, diabetic mice. "...

PMID:19364981|Circulation. 2009;119:2179-2187
..."We suggest that in addition to modulation of Ca(2+) influx, overstimulation of the cardiac mineralocorticoid pathway in the heart might be a major upstream factor for aberrant Ca(2+) release during diastole, which contributes to cardiac arrhythmia in heart failure."...

[All Refs in Pubmed]

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