Basic Informations of Adiponectin

Entrez Gene ID: 11450 [Pubmed]

UniProt Protein Name: Adiponectin

UniProt ID: Q60994


Related Drug:

No Related Drugs

References

PMID:18040027|Circulation. 2007;116:2809-2817
...The cardioprotective effects of short-term CR are mediated by increased production of adiponectin and the associated activation of AMP-activated protein kinase....

PMID:17339545|Circulation. 2007;115:1408-1416
...The present study demonstrates that adiponectin is a natural molecule that protects hearts from ischemia/reperfusion injury by inhibition of iNOS and nicotinamide adenine dinucleotide phosphate-oxidase protein expression and resultant oxidative/nitrative stress...

PMID:18040027|Circulation. 2007;116:2809-2817
...The cardioprotective effects of short-term CR are mediated by increased production of adiponectin and the associated activation of AMP-activated protein kinase....

PMID:18427128|Circulation. 2008;117:2253-2261
..." Expression of tumor necrosis factor-alpha, monocyte chemoattractant protein-1, plasminogen activator inhibitor type 1, and macrophage protein CD68 increased, and expression of adiponectin and peroxisome proliferator-activated receptor-gamma decreased in retroperitoneal adipose tissue from obese versus lean mice."...

PMID:18559699|Circulation. 2008;118:75-83
..."In contrast, atherosclerotic progression was almost completely inhibited by hepatic LOX-1 expression. In addition, plasma monocyte chemotactic protein-1 and lipid peroxide levels were decreased, whereas adiponectin was increased, suggesting decreased systemic oxidative stress. "...

PMID:19188503|Circulation. 2009;119:835-844
...Treatment of AMPK-DN mice with adiponectin failed to phosphorylate cardiac acetyl-CoA carboxylase as it did in WT mouse heart....

[All Refs in Pubmed]



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