Basic Informations of Adenosine receptor A2a

Entrez Gene ID: 11540 [Pubmed]

UniProt Protein Name: Adenosine receptor A2a

UniProt ID: Q60613


Related Drug:

DrugBank IDDrug Name
DB08770"4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol"
DB04932Defibrotide
DB01412Theobromine
DB01303Oxtriphylline
DB00806Pentoxifylline
DB00651Dyphylline
DB00640Adenosine
DB00358Mefloquine
DB00277Theophylline
DB00201Caffeine

References

PMID:16636171|Circulation. 2006;113:2120-2127
..."Our data epitomize the importance of vascular CD73 in limiting endothelial activation and monocyte recruitment via generation of adenosine acting through the A2A receptor, providing a molecular basis for therapeutic protection against vascular inflammation and neointimal hyperplasia."...

PMID:17060376|Circulation. 2006;114:2056-2064
...These results strongly suggest that the infarct-sparing effect of A2AR activation is primarily due to inhibition of CD4+ T-cell accumulation and activation in the reperfused heart...

[All Refs in Pubmed]



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