Basic Informations of Poly (ADP-ribose) polymerase family, member 1

Entrez Gene ID: 11545 [Pubmed]

UniProt Protein Name: Poly (ADP-ribose) polymerase family, member 1

UniProt ID: Q921K2


Related Drug:

DrugBank IDDrug Name
DB07787"5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE"
DB07330trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium
DB07232(2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium
DB07096"6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE"
DB040102-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide
DB03722"3,4-Dihydro-5-Methyl-Isoquinolinone"
DB035092-(4-Chlorophenyl)-5-Quinoxalinecarboxamide
DB030733-Methoxybenzamide
DB03072"2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone"
DB02701Nicotinamide
DB02690NU1025
DB02498Carba-Nicotinamide-Adenine-Dinucleotide

References

PMID:17438151|Circulation. 2007;115:2442-2450
..."PARP inhibition promoted an increase in collagen content, potentially through an increase in tissue inhibitor of metalloproteinase-2, and transmigration of smooth muscle cells to intima of atherosclerotic plaques as well as a decrease in monocyte chemotactic protein-1 production, all of which are markers of plaque stability. "...

[All Refs in Pubmed]



Network Situation

Node Details

The Selected Node Entrez Gene ID: ;
Protein Name:;

Expand Network with Neighbor Nodes

Click on Compounds Name to View Detail Descriptions
Num.Node NameNode Type
Relationships || Format: ||Change Views || Powered by Cytoscape Web

  • Tips
  • Click on Nodes to expand network with drugs and targets
  • See only TM or pp CVD network by reset with corresponding options
  • Highlight neighbor nodes just mouseover interested nodes
  • Find details of nodes and edges from tips when mouseover
  • Drag nodes or Zoom the network with panel in the bottom-right
  • Nodes and Edges
  • NodesType
    Blue RectTargets
    Yellow RectExpand Targets
    White borderTargets have drug
    Red VeeDrugs
    EdgesType
    Blue Text mining
    Red PPI