Basic Informations of Advanced glycation end-products receptor

Entrez Gene ID: 11596 [Pubmed]

UniProt Protein Name: Advanced glycation end-products receptor

UniProt ID: O35444

Related Drug:

No Related Drugs


PMID:16505177|Circulation. 2006;113:1226-1234
...These findings demonstrate novel and key roles for RAGE in I/R injury in the heart. The findings also demonstrate that the interaction of RAGE with advanced-glycation end products affects myocardial energy metabolism and function during I/R....

PMID:17420349|Circulation. 2007;115:2178-2187
..."Quantitative reverse-transcription polymerase chain reaction analysis showed increased expression of receptors for advanced glycation end products (RAGE), vascular cell adhesion molecule-1, vascular endothelial growth factor, and connective tissue growth factor."...

PMID:18574060|Circulation. 2008;117:3216-3226
..."HMGB1 plays a major role in the early event of I/R injury by binding to RAGE, resulting in the activation of proinflammatory pathways and enhanced myocardial injury. "...

PMID:19620505|Circulation. 2009;120:427-436
..."Myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) are members of the S100 family of calcium-modulated proteins that regulate myeloid cell function and control inflammation, in part, through activation of Toll-like receptor-4 and the receptor for advanced glycation end products. "...

[All Refs in Pubmed]

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