Basic Informations of Type-1A angiotensin II receptor

Entrez Gene ID: 11607 [Pubmed]

UniProt Protein Name: Type-1A angiotensin II receptor

UniProt ID: P29754

Related Drug:

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PMID:16585392|Circulation. 2006;113:1787-1798
...We investigated the role of the RAS in WT-p90RSK-Tg animals after ischemia/reperfusion with the use of an ACE-I (captopril) and an angiotensin II type 1 receptor blocker (olmesartan). ...

PMID:18413498|Circulation. 2008;117:2211-2223
..."Importantly, activation of the renin-angiotensin system was noted in the triply n/i/eNOS(-/-) mice, and long-term oral treatment with an angiotensin II type 1 receptor blocker significantly suppressed coronary arteriosclerotic lesion formation and the occurrence of spontaneous myocardial infarction and improved the prognosis of those mice, along with ameliorating the metabolic abnormalities."...

PMID:19506106|Circulation. 2009;119:3125-3132
..." Pretreatment with rosiglitazone inhibited the Ang II-induced expression of angiotensin type 1a Ang II receptor while having no effect on the angiotensin type 2 Ang II receptor, in addition to reducing Ang II-induced expression of E-selectin, tumor necrosis factor-alpha, and interleukin-6."...

[All Refs in Pubmed]

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