Basic Informations of Transforming protein RhoA

Entrez Gene ID: 11848 [Pubmed]

UniProt Protein Name: Transforming protein RhoA

UniProt ID: Q9QUI0

Related Drug:

No Related Drugs


PMID:20083679|Circulation. 2010;121:537-548
..."CO enhanced EC proliferation via rapid activation of RhoA (Ras homolog gene family, member A), followed by downstream phosphorylation of Akt, endothelial nitric oxide (NO) synthase phosphorylation, and a 60% increase in NO generation by ECs. "...

PMID:18316486|Circulation. 2008;117:1423-1435
..."Our results identify Shp2 as the first PTP with a critical role in adult cardiac function, indicate that in the absence of Shp2 cardiac hypertrophy does not occur in response to pressure overload, and demonstrate that the cardioprotective role of Shp2 is mediated via control of both the Erk/MAPK and RhoA signaling pathways."...

[All Refs in Pubmed]

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