Basic Informations of Inhibitor of nuclear factor kappa-B kinase subunit alpha

Entrez Gene ID: 12675 [Pubmed]

UniProt Protein Name: Inhibitor of nuclear factor kappa-B kinase subunit alpha

UniProt ID: E9Q605


Related Drug:

DrugBank IDDrug Name
DB00795Sulfasalazine
DB00244Mesalazine
DB00233Aminosalicylic Acid

References

PMID:17030682|Circulation. 2006;114:1838-1846
..."Treatment with sorbinil blunted the activation of protein kinase C, c-Jun NH2-terminal kinase, and p38, as well as phosphorylation of interleukin receptor-associated kinase, IkappaB-alpha, IkappaB kinase complex-alpha/beta, and phospholipase-gamma1 and -beta1."...

PMID:20212283|Circulation. 2010;121:1338-1346
..."The severity of aneurysm among these 3 groups positively correlates with C9 deposition, and/or the activities of MMP2 and MMP9, and/or the levels of phosphorylated c-Jun, c-Fos, IKK-alpha/beta, and p65."...

[All Refs in Pubmed]



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