Basic Informations of Suppressor of cytokine signaling 3

Entrez Gene ID: 12702 [Pubmed]

UniProt Protein Name: Suppressor of cytokine signaling 3

UniProt ID: O35718

Related Drug:

No Related Drugs


PMID:16820587|Circulation. 2006;114[suppl I]:I-282–I-289
..."Furthermore, WT females expressed more of the suppressor of cytokine signaling protein 3 after I/R, which may in part explain TNFR1 signaling resistance in the female myocardium."...

PMID:17101849|Circulation. 2006;114:2364-2373
...SOCS3-mediated regulation of gp130 signaling can affect susceptibility to viral infection in the heart....

PMID:22082679|Circulation. 2011;124:2690-2701
...We generated cardiac-specific SOCS3 knockout (SOCS3 cKO) mice. ...

PMID:18824767|Circulation. 2008;118[suppl 1]:S38–S45
..."The deleterious effects of TNFR2 ablation were associated with a decrease in mRNA and protein levels of SOCS3, STAT3, and vascular endothelial growth factor as well as an increase in myocardial interleukin-1-beta production in female hearts. "...

[All Refs in Pubmed]

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