Basic Informations of C-C chemokine receptor type 2

Entrez Gene ID: 12772 [Pubmed]

UniProt Protein Name: C-C chemokine receptor type 2

UniProt ID: P51683


Related Drug:

No Related Drugs

References

PMID:21730304|Circulation. 2011;124:454-464
..."Finally, there were 3.6- and 2.4-fold increases in Ly6-C(high) and CC-chemokine receptor 2-positive cells in lesions of apoE(-/-) MΦLRP1(-/-) versus apoE(-/-) mice, suggesting that accumulation of apoptotic cells enhances lesion development and macrophage content by promoting the recruitment of inflammatory monocytes."...

PMID:18165355|Circulation. 2008;117:1642-1648
..." Deletion of CX3CL1 did not reduce the number of circulating monocytes in either ""wild-type"" ApoE(-/-) mice or CCR2(-/-)ApoE(-/-) mice, which suggests a role for CX3CL1 in the direct recruitment and/or capture of CCR2-deficient monocytes."...

PMID:18824773|Circulation. 2008;118[suppl 1]:S71–S77
...These findings highlight the importance of MCP-1/CCR2 signaling in the response to vascular injury and identify novel pathways linking endothelial BH4 to inflammation and vascular remodeling....

[All Refs in Pubmed]



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