Basic Informations of C-C chemokine receptor type 5

Entrez Gene ID: 12774 [Pubmed]

UniProt Protein Name: C-C chemokine receptor type 5

UniProt ID: P51682

Related Drug:

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PMID:17893273|Circulation. 2007;116:1812-1820
..."A reduction of lesion formation by YB-1 knockdown was not observed in apolipoprotein E-deficient mice deficient in the CCL5 receptor CCR5 or after treatment with the CCL5 antagonist Met-RANTES, which indicates that YB-1 effects were dependent on CCL5."...

PMID:18347211|Circulation. 2008;117:1649-1657
..."CCL2, CX3CR1, and CCR5 play independent and additive roles in atherogenesis. Signals mediated through these pathways critically determine the frequency of circulating monocyte subsets and thereby account for almost all macrophage accumulation into atherosclerotic arteries."...

[All Refs in Pubmed]

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