Basic Informations of Estrogen receptor beta

Entrez Gene ID: 13983 [Pubmed]

UniProt Protein Name: Estrogen receptor beta

UniProt ID: O08537


Related Drug:

DrugBank IDDrug Name
DB08020"(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL"
DB07933"(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL"
DB07757"(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one"
DB07702"(16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL"
DB07638"(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL"
DB072363-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL
DB072303-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE
DB071985-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
DB071504-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
DB071191-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL
DB07036"(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol"
DB070322-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL
DB07009"2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL"
DB06937"4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL"
DB06927[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
DB068753-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE
DB06832"2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL"
DB04574Estropipate
DB04573Estriol
DB04020"4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol"
DB03882"5-Alpha-Androstane-3-Beta,17beta-Diol"
DB03860"N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide"
DB02983Para-Mercury-Benzenesulfonic Acid
DB01645Genistein
DB01196Estramustine
DB01108Trilostane
DB00783Estradiol
DB00675Tamoxifen
DB00481Raloxifene
DB00255Diethylstilbestrol

References

PMID:17088460|Circulation. 2006;114:2261-2270
...Both ER alpha and ER beta contribute to E2-mediated EPC activation and tissue incorporation and to preservation of cardiac function after myocardial infarction....

PMID:17562954|Circulation. 2007;115:3197-3204
...no details...

PMID:19581491|Circulation. 2009;120:245-254
..."The activation of ER-beta by DPN treatment leads to increased protein SNO and cardioprotection against ischemia/reperfusion injury, suggesting that long-term estrogen exposure protects hearts largely via activation of ER-beta and nitric oxide/SNO signaling."...

[All Refs in Pubmed]



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