Basic Informations of Transcription factor GATA-4

Entrez Gene ID: 14463 [Pubmed]

UniProt Protein Name: Transcription factor GATA-4

UniProt ID: Q08369


Related Drug:

No Related Drugs

References

PMID:16461841|Circulation. 2006;113:679-690
..." One of the intrinsic histone acetyltransferases, p300, serves as a coactivator of hypertrophy-responsive transcriptional factors such as a cardiac zinc finger protein GATA-4 and is involved in its hypertrophic stimulus-induced acetylation and DNA binding. "...

PMID:18316483|Circulation. 2008;117:1414-1422
..." Analysis of the expression of transcription factors required for cardiogenesis revealed downregulation of key cardiac transcription factors such as the serum response factor, Gata4, and Nkx2-5."...

PMID:19332462|Circulation. 2009;119:1941-1949
..." In addition, the ALDH2 transgene significantly attenuated chronic alcohol intake-induced myocardial fibrosis, protein carbonyl formation, apoptosis, enhanced NADPH oxidase p47(phox) and calcineurin expression, as well as phosphorylation of ASK-1, GSK-3beta, GATA4, and CREB."...

[All Refs in Pubmed]



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