Basic Informations of Heme oxygenase 1

Entrez Gene ID: 15368 [Pubmed]

UniProt Protein Name: Heme oxygenase 1

UniProt ID: P14901


Related Drug:

DrugBank IDDrug Name
DB073421-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
DB06914"1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE"
DB04803Verdoheme
DB039062-Phenylheme
DB03014Heme
DB0246812-Phenylheme
DB02073Biliverdine Ix Alpha
DB01942Formic Acid
DB00157NADH

References

PMID:20404253|Circulation. 2010;121:1912-1925
..."Augmentation of HO-1 or its product, CO, may represent a novel therapeutic strategy for ameliorating HF."...

PMID:21518986|Circulation. 2011;123:1986-1995
..."In contrast, a 7-day doxycycline treatment sustained high heme oxygenase-1 levels during the entire period of hypoxic inflammation, inhibited macrophage accumulation and activation, induced macrophage interleukin-10 expression, and prevented the development of HPH. "...

PMID:19487598|Circulation. 2009;119:3017-3027
..."HO-1 expression levels correlated with the plaque destabilizing factors matrix metalloproteinase-9, interleukin-8, and interleukin-6. "...

PMID:19752329|Circulation. 2009;120:1222-1230
...These results also reveal an important role of nuclear factor-kappaB in both basal and iNOS-induced expression of cardiac HO-1. ...

[All Refs in Pubmed]



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