Basic Informations of Intercellular adhesion molecule 1

Entrez Gene ID: 15894 [Pubmed]

UniProt Protein Name: Intercellular adhesion molecule 1

UniProt ID: P13597

Related Drug:

DrugBank IDDrug Name


PMID:16818815|Circulation. 2006;114:150-159
..."Here, we report that endogenous integrin-linked kinase (ILK) is a novel molecule that responds to hypoxia in ECs that regulates the expression of stromal cell-derived factor-1 (SDF-1) and intercellular adhesion molecule-1 (ICAM-1) through nuclear factor-kappaB and hypoxia-inducible factor-1alpha and induces recruitment of EPCs to ischemic areas"...

PMID:20048211|Circulation. 2010; 121: 315-324
..."EOC adhesion to fibronectin, fibrinogen, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 under flow conditions, as well as their transmigration toward stromal cell-derived factor-1alpha, was dose-dependently reduced after preincubation with recombinant human sCD40L for 24 hours."...

PMID:20176988|Circulation. 2010;121:1124-1133
..."CD137 signaling promoted the production of inflammatory molecules, including monocyte chemoattractant protein-1, interleukin-6, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1, in endothelial cells. "...

PMID:20421522|Circulation. 2010;121:2033-2044
..."Impaired adhesion coincided with reduced cell spreading, actin polymerization, and CD29 expression in macrophages, as well as decreased expression of the adhesion molecules intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in endothelial cells. "...

PMID:21576651|Circulation. 2011;123:2404-2413
..."Similarly, the in vitro adhesion of isolated mouse monocytes to tumor necrosis factor α--stimulated murine endothelial cell monolayers and their migration across the cell layers were strongly reduced in P2Y(1)-deficient compared with wild-type endothelial cells, as was the expression of the adhesion molecules P-selectin, Vascular cell adhesion molecule 1, and intercellular adhesion molecule 1."...

[All Refs in Pubmed]

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