Basic Informations of C-X-C motif chemokine 10

Entrez Gene ID: 15945 [Pubmed]

UniProt Protein Name: C-X-C motif chemokine 10

UniProt ID: P17515

Related Drug:

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PMID:16682613|Circulation. 2006;113:2301-2312
...We provide novel evidence for a functional role for the effector T-cell chemoattractant CXCL10 in atherosclerotic lesion formation by modulating the local balance of the effector and regulatory arms of the immune system...

PMID:16940188|Circulation. 2006;114:1293-1300
..."Besides inhibiting IFN-gamma responses, heparin has further immunomodulatory effects by competing for binding with IP-10, I-TAC, and Mig on endothelial cells. "...

PMID:19139386|Circulation. 2009;119:426-435
..."The present study defines a novel pathway in which interferon-gamma and its effector, CXCL10, contribute to divergent pathways in abdominal aortic aneurysm versus plaque formation, inhibiting the former pathology but promoting the latter. "...

[All Refs in Pubmed]

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