Basic Informations of Integrin-linked protein kinase

Entrez Gene ID: 16202 [Pubmed]

UniProt Protein Name: Integrin-linked protein kinase

UniProt ID: O55222


Related Drug:

No Related Drugs

References

PMID:16818815|Circulation. 2006;114:150-159
..."Here, we report that endogenous integrin-linked kinase (ILK) is a novel molecule that responds to hypoxia in ECs that regulates the expression of stromal cell-derived factor-1 (SDF-1) and intercellular adhesion molecule-1 (ICAM-1) through nuclear factor-kappaB and hypoxia-inducible factor-1alpha and induces recruitment of EPCs to ischemic areas"...

PMID:17088456|Circulation. 2006;114:2271-2279
..."This increase in ILK was associated with activation of the Rho family guanine triphosphatases, Rac1 and Cdc42, and known hypertrophic signaling kinases, including extracellular signal-related kinases (ERK1/2) and p70 S6 kinase. "...

[All Refs in Pubmed]



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