Basic Informations of Transcription factor AP-1

Entrez Gene ID: 16476 [Pubmed]

UniProt Protein Name: Transcription factor AP-1

UniProt ID: P05627

Related Drug:

DrugBank IDDrug Name
DB01169Arsenic trioxide


PMID:17030682|Circulation. 2006;114:1838-1846
..."These changes were associated with decreased myocardial nuclear factor-kappaB and activating protein-1 activity, prostaglandin E2 production, induction of cyclooxygenase 2, and inducible nitric oxide synthase"...

PMID:20212283|Circulation. 2010;121:1338-1346
..." Furthermore, we demonstrated that the membrane attack complex directly induced gene expression of matrix metalloproteinase-2 and -9 in vitro, which required activation of the activator protein-1 and nuclear factor-kappaB signaling pathways."...

[All Refs in Pubmed]

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