Basic Informations of Nitric oxide synthase, brain

Entrez Gene ID: 18125 [Pubmed]

UniProt Protein Name: Nitric oxide synthase, brain

UniProt ID: Q9Z0J4


Related Drug:

DrugBank IDDrug Name
DB08019"N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine"
DB08018"N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE"
DB04223Nitroarginine
DB038925-N-Allyl-Arginine
DB03710N5-(1-Imino-3-Butenyl)-L-Ornithine
DB03707S-Ethyl-N-Phenyl-Isothiourea
DB034612'-Monophosphoadenosine 5'-Diphosphoribose
DB03449N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine
DB03247Riboflavin Monophosphate
DB03147Flavin-Adenine Dinucleotide
DB03144N-Omega-Hydroxy-L-Arginine
DB03014Heme
DB02991S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea
DB02944Alpha-D-Mannose
DB02727N-Butyl-N'-Hydroxyguanidine
DB02692"(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin"
DB02644N-Omega-Propyl-L-Arginine
DB02143N-Isopropyl-N'-Hydroxyguanidine
DB02077L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide
DB02044N-(3-(Aminomethyl)Benzyl)Acetamidine
DB02027N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine
DB019973-Bromo-7-Nitroindazole
DB01942Formic Acid
DB01821"L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide"
DB00155L-Citrulline

References

PMID:17242280|Circulation. 2007;115:483-492
...These data demonstrate the physiological relevance of the interaction between PMCA4b and nNOS and suggests its signaling role in the heart....

PMID:20921441|Circulation. 2010;122:1588-1603
...nNOS translocation into the mitochondria was dependent on heat shock protein 90....

PMID:18413498|Circulation. 2008;117:2211-2223
..."Importantly, activation of the renin-angiotensin system was noted in the triply n/i/eNOS(-/-) mice, and long-term oral treatment with an angiotensin II type 1 receptor blocker significantly suppressed coronary arteriosclerotic lesion formation and the occurrence of spontaneous myocardial infarction and improved the prognosis of those mice, along with ameliorating the metabolic abnormalities."...

PMID:18541744|Circulation. 2008;117:3187-3198
...Cardiomyocyte NOS1 may be a useful target against cardiac deterioration during chronic pressure-overload-induced HF through modulation of calcium cycling....

PMID:19770398|Circulation. 2009;120:1345-1354
...Deficiency in nNOS increases ventricular arrhythmia and mortality after MI in mice. ...

[All Refs in Pubmed]



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