Basic Informations of Neurogenic locus notch homolog protein 1

Entrez Gene ID: 18128 [Pubmed]

UniProt Protein Name: Neurogenic locus notch homolog protein 1

UniProt ID: Q01705

Related Drug:

No Related Drugs


PMID:20176991|Circulation. 2010;121:1104-1112
..."Cholesterol enhanced the messenger RNA expression (quantitative, real-time reverse-transcription polymerase chain reaction) of vascular endothelial growth factor and inhibited Notch1 messenger RNA expression in both ApoE(-/-) and WT EPCs, whereas endothelial nitric oxide synthase messenger RNA expression increased in ApoE(-/-) EPCs and declined in WT EPCs after cholesterol exposure. "...

PMID:19433762|Circulation. 2009;119:2686-2692
..."These findings indicate that Notch1, rather than Notch3, mediates SMC proliferation and neointimal formation after vascular injury through CHF1/Hey2 and suggest that therapies that target Notch1/CHF1/Hey2 in SMCs may be beneficial in preventing vascular proliferative diseases."...

[All Refs in Pubmed]

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