Basic Informations of Tyrosine-protein phosphatase non-receptor type 11

Entrez Gene ID: 19247 [Pubmed]

UniProt Protein Name: Tyrosine-protein phosphatase non-receptor type 11

UniProt ID: P35235

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PMID:18316486|Circulation. 2008;117:1423-1435
..."Our results identify Shp2 as the first PTP with a critical role in adult cardiac function, indicate that in the absence of Shp2 cardiac hypertrophy does not occur in response to pressure overload, and demonstrate that the cardioprotective role of Shp2 is mediated via control of both the Erk/MAPK and RhoA signaling pathways."...

[All Refs in Pubmed]

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