Basic Informations of Transcription factor p65

Entrez Gene ID: 19697 [Pubmed]

UniProt Protein Name: Transcription factor p65

UniProt ID: Q04207


Related Drug:

No Related Drugs

References

PMID:16820585|Circulation. 2006;114[suppl I]:I-270–I-274
...no details...

PMID:16818815|Circulation. 2006;114:150-159
...no details...

PMID:16908774|Circulation. 2006;114:830-837
..."This cardiac-protective effect is mediated by paracrine ET-4 modulation of TNF-related apoptosis, in part through upregulation of NF-kappaB signaling."...

PMID:17030682|Circulation. 2006;114:1838-1846
...The results of the present study show that pharmacological inhibition of aldose reductase by sorbinil or knockdown of the enzyme by small interfering RNA prevents the activation of nuclear factor-kappaB and the release of tumor necrosis factor-alpha from lipopolysaccharide-stimulated RAW264.7 or H9c2 cells...

PMID:17389268|Circulation. 2007;115:1885-1894
...no details...

PMID:17438151|Circulation. 2007;115:2442-2450
..."In PARP-1(-/-) macrophages, monocyte chemotactic protein-1 expression was severely inhibited because of a defective nuclear factor-kappaB nuclear translocation in response to lipopolysaccharide"...

PMID:17785622|Circulation. 2007;116: 1577-1584
...no details...

PMID:20212283|Circulation. 2010;121:1338-1346
..."The severity of aneurysm among these 3 groups positively correlates with C9 deposition, and/or the activities of MMP2 and MMP9, and/or the levels of phosphorylated c-Jun, c-Fos, IKK-alpha/beta, and p65."...

PMID:21242479|Circulation. 2011;123:400-408
...no details...

PMID:21747053|Circulation. 2011;124:406-415
...no details...

PMID:18574060|Circulation. 2008;117:3216-3226
...no details...

PMID:19255345|Circulation. 2009;119:1386-1397
..."Compared with sham, WT HF hearts exhibited significant remodeling with robust activation of nuclear factor (NF)-kappaB, p38 mitogen-activated protein kinase, and JNK2 and upregulation of TNF, interleukin (IL)-1beta, IL-6, and IL-10. "...

PMID:19752329|Circulation. 2009;120:1222-1230
...no details...

PMID:19770394|Circulation. 2009;120:1401-1414
...no details...

[All Refs in Pubmed]



Network Situation

Node Details

The Selected Node Entrez Gene ID: ;
Protein Name:;

Expand Network with Neighbor Nodes

Click on Compounds Name to View Detail Descriptions
Num.Node NameNode Type
Relationships || Format: ||Change Views || Powered by Cytoscape Web

  • Tips
  • Click on Nodes to expand network with drugs and targets
  • See only TM or pp CVD network by reset with corresponding options
  • Highlight neighbor nodes just mouseover interested nodes
  • Find details of nodes and edges from tips when mouseover
  • Drag nodes or Zoom the network with panel in the bottom-right
  • Nodes and Edges
  • NodesType
    Blue RectTargets
    Yellow RectExpand Targets
    White borderTargets have drug
    Red VeeDrugs
    EdgesType
    Blue Text mining
    Red PPI