Basic Informations of Vascular cell adhesion protein 1

Entrez Gene ID: 22329 [Pubmed]

UniProt Protein Name: Vascular cell adhesion protein 1

UniProt ID: P29533

Related Drug:

No Related Drugs


PMID:17420349|Circulation. 2007;115:2178-2187
..."Quantitative reverse-transcription polymerase chain reaction analysis showed increased expression of receptors for advanced glycation end products (RAGE), vascular cell adhesion molecule-1, vascular endothelial growth factor, and connective tissue growth factor."...

PMID:20048211|Circulation. 2010; 121: 315-324
..."EOC adhesion to fibronectin, fibrinogen, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 under flow conditions, as well as their transmigration toward stromal cell-derived factor-1alpha, was dose-dependently reduced after preincubation with recombinant human sCD40L for 24 hours."...

PMID:20176988|Circulation. 2010;121:1124-1133
..."CD137 signaling promoted the production of inflammatory molecules, including monocyte chemoattractant protein-1, interleukin-6, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1, in endothelial cells. "...

PMID:20421522|Circulation. 2010;121:2033-2044
..."Impaired adhesion coincided with reduced cell spreading, actin polymerization, and CD29 expression in macrophages, as well as decreased expression of the adhesion molecules intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in endothelial cells. "...

PMID:20733098|Circulation. 2010;122:1026-1036
...One-week treatment with C5aRA or anti-C5aR-blocking monoclonal antibody limited neointimal hyperplasia and inflammatory cell content and was associated with reduced vascular cell adhesion molecule-1 expression. ...

PMID:21576651|Circulation. 2011;123:2404-2413
..."Similarly, the in vitro adhesion of isolated mouse monocytes to tumor necrosis factor α--stimulated murine endothelial cell monolayers and their migration across the cell layers were strongly reduced in P2Y(1)-deficient compared with wild-type endothelial cells, as was the expression of the adhesion molecules P-selectin, Vascular cell adhesion molecule 1, and intercellular adhesion molecule 1."...

PMID:18663083|Circulation. 2008;118:754-763
..."At 30 weeks, the aortic sinus lesions in P2Y(1)(-/-)/ApoE(-/-) mice were still diminished in size and displayed reduced inflammation, reflected by decreased macrophage infiltration and diminished VCAM-1 immunostaining, compared with those in ApoE(-/-) mice. They also had a lower smooth muscle cell content."...

PMID:19433759|Circulation. 2009;119:2708-2717
..."Deficiency of CD11c decreased firm arrest of mouse monocytes on vascular cell adhesion molecule-1 and E-selectin in a shear flow assay, reduced monocyte/macrophage accumulation in atherosclerotic lesions, and decreased atherosclerosis development in apoE-/- mice on a high-fat diet."...

[All Refs in Pubmed]

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