Basic Informations of 5-nucleotidase

Entrez Gene ID: 23959 [Pubmed]

UniProt Protein Name: 5-nucleotidase

UniProt ID: Q61503


Related Drug:

No Related Drugs

References

PMID:16636171|Circulation. 2006;113:2120-2127
..."Our data epitomize the importance of vascular CD73 in limiting endothelial activation and monocyte recruitment via generation of adenosine acting through the A2A receptor, providing a molecular basis for therapeutic protection against vascular inflammation and neointimal hyperplasia."...

PMID:17353435|Circulation. 2007;115:1581-1590
..."Taken together, pharmacological and genetic evidence demonstrate the importance of CD73-dependent adenosine generation and signaling through A2B AR for cardioprotection by ischemic preconditioning and suggests 5'-nucleotidase or A2B AR agonists as therapy for myocardial ischemia."...

[All Refs in Pubmed]



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