Basic Informations of CREB-regulated transcription coactivator 1

Entrez Gene ID: 382056 [Pubmed]

UniProt Protein Name: CREB-regulated transcription coactivator 1

UniProt ID: Q68ED7

Related Drug:

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PMID:19103994|Circulation. 2009;119:79-88
..."Transcriptome and proteome analysis revealed a set of predicted CREB/CREM target genes including the cardiac ryanodine receptor, tropomyosin 1alpha, and cardiac alpha-actin as altered on the mRNA or protein level along with the improved phenotype in CREM-deficient beta(1)AR-transgenic hearts."...

PMID:19332462|Circulation. 2009;119:1941-1949
..." In addition, the ALDH2 transgene significantly attenuated chronic alcohol intake-induced myocardial fibrosis, protein carbonyl formation, apoptosis, enhanced NADPH oxidase p47(phox) and calcineurin expression, as well as phosphorylation of ASK-1, GSK-3beta, GATA4, and CREB."...

[All Refs in Pubmed]

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