Basic Informations of Forkhead box protein O1

Entrez Gene ID: 56458 [Pubmed]

UniProt Protein Name: Forkhead box protein O1

UniProt ID: Q9R1E0

Related Drug:

No Related Drugs


PMID:16952979|Circulation. 2006;114:1159-1168
..." In addition, both Foxo1 and Foxo3 are phosphorylated and consequently inactivated in hearts undergoing hypertrophic growth induced by hemodynamic stress."...

PMID:16952980|Circulation. 2006;114:1269-1276
..."Our results provide the first evidence that specific TFs identified in murine models (MEF2, NKX, NFAT, and GATA) are associated with human heart failure. Moreover, these data implicate specific members of the FOX family of TFs (FOXC1, C2, P1, P4, and O1A) not previously suggested in heart failure pathogenesis."...

PMID:21060073|Circulation. 2010;122:2170-2182
...Sirt1 plays an important role in mediating I/R-induced increases in the nuclear localization of FoxO1 in vivo....

[All Refs in Pubmed]

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