Basic Informations of Apoptosis-associated speck-like protein containing a CARD

Entrez Gene ID: 66824 [Pubmed]

UniProt Protein Name: Apoptosis-associated speck-like protein containing a CARD

UniProt ID: Q9EPB4

Related Drug:

No Related Drugs


PMID:21282498|Circulation. 2011;123:594-604
..."In mice deficient for apoptosis-associated speck-like adaptor protein and caspase-1, these inflammatory responses and subsequent injuries, including infarct development and myocardial fibrosis and dysfunction, were markedly diminished."...

PMID:18541743|Circulation. 2008;117: 3079-3087
...Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is an adaptor protein that regulates caspase-1-dependent IL-1 beta and IL-18 generation; ...

[All Refs in Pubmed]

Network Situation

Node Details

The Selected Node Entrez Gene ID: ;
Protein Name:;

Expand Network with Neighbor Nodes

Click on Compounds Name to View Detail Descriptions
Num.Node NameNode Type
Relationships || Format: ||Change Views || Powered by Cytoscape Web

  • Tips
  • Click on Nodes to expand network with drugs and targets
  • See only TM or pp CVD network by reset with corresponding options
  • Highlight neighbor nodes just mouseover interested nodes
  • Find details of nodes and edges from tips when mouseover
  • Drag nodes or Zoom the network with panel in the bottom-right
  • Nodes and Edges
  • NodesType
    Blue RectTargets
    Yellow RectExpand Targets
    White borderTargets have drug
    Red VeeDrugs
    Blue Text mining
    Red PPI