Compounds Details

back to menu

水杨酸

Salicylic acid

powered by Marvin. Double Click on the chemical would show a detailed plugin for structural view


Chemical Informations

DescriptorsValueThreshold
Molecular Weight:138.13500
Number of H acceptors:310
Number of H donors:25
Number of Rotatable bond:110
octanol-water partition coefficient Log p:1.1675

Source TCMs:

北沙参, 大青叶, 青黛, 板蓝根, 茵陈, 络石藤, 桑椹, 黄精, 广东紫珠, 广枣, 覆盆子, 广金钱草, etc...

Potential Target

ScoreTargetNameFunction
0.878 290 Prostaglandin G/H synthase 2 Involved in peroxidase activity
0.87 20 Prostaglandin G/H synthase 1 Involved in peroxidase activity
0.854 139 Aldo-keto reductase family 1 member C1 Involved in oxidoreductase activity
0.79 275 Arachidonate 5-lipoxygenase Involved in oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.782 686 Aldo-keto reductase family 1 member C2 Involved in oxidoreductase activity
0.776 650 Aldo-keto reductase family 1 member C3 Involved in oxidoreductase activity
0.75 828 Phenylalanine-4-hydroxylase Amino acid transport and metabolism
0.746 76 Nitric-oxide synthase, brain Inorganic ion transport and metabolism
0.742 186 Glutamate--cysteine ligase catalytic subunit Involved in glutamate-cysteine ligase activity
0.74 389 Amiloride-sensitive cation channel 2, neuronal Involved in amiloride-sensitive sodium channel activity
0.74 1714 Mitogen-activated protein kinase 3 Involved in MAP kinase activity
0.74 6109 DNA polymerase epsilon catalytic subunit A Replication, recombination and repair
0.738 242 Asparagine synthetase [glutamine-hydrolyzing] Amino acid transport and metabolism
0.738 669 Asparaginyl-tRNA synthetase, cytoplasmic Translation, ribosomal structure and biogenesis
0.736 2155 Insulin-degrading enzyme Posttranslational modification, protein turnover, chaperones
0.734 3949 Prolyl 3-hydroxylase 2 Not Available
0.734 4061 Peroxisomal sarcosine oxidase Amino acid transport and metabolism
0.732 97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Involved in oxidoreductase activity
0.728 937 Proto-oncogene tyrosine-protein kinase LCK Involved in protein kinase activity
0.728 6105 3-oxo-5-beta-steroid 4-dehydrogenase Involved in aldo-keto reductase activity
0.724 775 Acetyl-CoA carboxylase 2 Lipid transport and metabolism
0.724 3904 Alanine aminotransferase 2 Amino acid transport and metabolism
0.722 412 Peroxisomal carnitine O-octanoyltransferase Involved in acyltransferase activity
0.722 701 Isoleucine-tRNA synthetase Translation, ribosomal structure and biogenesis
0.72 182 2-oxoglutarate dehydrogenase E1 component, mitochondrial Energy production and conversion
0.72 4000 Prolyl 4-hydroxylase subunit alpha-2 Not Available
0.718 54 Prothrombin Involved in blood clotting cascade
0.718 280 4-aminobutyrate aminotransferase, mitochondrial Amino acid transport and metabolism
0.716 21 Beta-adrenergic receptor kinase 2 Involved in G-protein coupled receptor kinase activity
0.716 822 Aldose reductase Involved in oxidoreductase activity
0.716 1176 Mitogen-activated protein kinase 1 Involved in MAP kinase activity
0.714 4047 Diacylglycerol kinase gamma Lipid transport and metabolism
0.712 210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase Translation, ribosomal structure and biogenesis
0.712 803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial Energy production and conversion
0.712 3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 Not Available
0.71 90 Tryptophan 5-hydroxylase 2 Amino acid transport and metabolism
0.71 997 Protein kinase C beta type Involved in protein serine/threonine kinase activity
0.71 4066 Protein-arginine deiminase type-1 Not Available
0.708 261 Threonyl-tRNA synthetase, cytoplasmic Translation, ribosomal structure and biogenesis
0.708 508 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Involved in nucleic acid binding
0.708 2180 3-phosphoinositide-dependent protein kinase 1 Involved in protein kinase activity
0.706 209 Aspartoacylase Amino acid transport and metabolism
0.706 934 Proto-oncogene tyrosine-protein kinase Fyn Involved in protein kinase activity
0.704 388 AMP deaminase 1 Involved in deaminase activity
0.704 1064 DNA (cytosine-5)-methyltransferase 1 Replication, recombination and repair
0.704 1970 Protein kinase C alpha type Involved in protein serine/threonine kinase activity
0.704 6288 Low molecular weight phosphotyrosine protein phosphatase Signal transduction mechanisms
0.702 67 Prolyl 4-hydroxylase subunit alpha-1 Involved in oxidoreductase activity
0.702 774 Cysteinyl-tRNA synthetase, cytoplasmic Translation, ribosomal structure and biogenesis
0.702 1596 Protein-glutamine gamma-glutamyltransferase 2 Involved in protein-glutamine gamma-glutamyltransferase activity
0.702 3964 Trimethyllysine dioxygenase, mitochondrial Secondary metabolites biosynthesis, transport and catabolism
0.702 6621 Methionine aminopeptidase 1 Translation, ribosomal structure and biogenesis
0.7 2592 Beta-galactosidase Carbohydrate transport and metabolism
0.7 3448 Thromboxane-A synthase Secondary metabolites biosynthesis, transport and catabolism
0.7 3924 Phospholipase D1 Lipid transport and metabolism
0.7 4042 Glutathione transferase omega-2 Posttranslational modification, protein turnover, chaperones
0.878 290 Prostaglandin G/H synthase 2 Involved in peroxidase activity
0.87 20 Prostaglandin G/H synthase 1 Involved in peroxidase activity
0.854 139 Aldo-keto reductase family 1 member C1 Involved in oxidoreductase activity
0.79 275 Arachidonate 5-lipoxygenase Involved in oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.782 686 Aldo-keto reductase family 1 member C2 Involved in oxidoreductase activity
0.776 650 Aldo-keto reductase family 1 member C3 Involved in oxidoreductase activity
0.75 828 Phenylalanine-4-hydroxylase Amino acid transport and metabolism
0.746 76 Nitric-oxide synthase, brain Inorganic ion transport and metabolism
0.742 186 Glutamate--cysteine ligase catalytic subunit Involved in glutamate-cysteine ligase activity
0.74 389 Amiloride-sensitive cation channel 2, neuronal Involved in amiloride-sensitive sodium channel activity
0.74 1714 Mitogen-activated protein kinase 3 Involved in MAP kinase activity
0.74 6109 DNA polymerase epsilon catalytic subunit A Replication, recombination and repair
0.738 242 Asparagine synthetase [glutamine-hydrolyzing] Amino acid transport and metabolism
0.738 669 Asparaginyl-tRNA synthetase, cytoplasmic Translation, ribosomal structure and biogenesis
0.736 2155 Insulin-degrading enzyme Posttranslational modification, protein turnover, chaperones
0.734 3949 Prolyl 3-hydroxylase 2 Not Available
0.734 4061 Peroxisomal sarcosine oxidase Amino acid transport and metabolism
0.732 97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Involved in oxidoreductase activity
0.728 937 Proto-oncogene tyrosine-protein kinase LCK Involved in protein kinase activity
0.728 6105 3-oxo-5-beta-steroid 4-dehydrogenase Involved in aldo-keto reductase activity
0.724 775 Acetyl-CoA carboxylase 2 Lipid transport and metabolism
0.724 3904 Alanine aminotransferase 2 Amino acid transport and metabolism
0.722 412 Peroxisomal carnitine O-octanoyltransferase Involved in acyltransferase activity
0.722 701 Isoleucine-tRNA synthetase Translation, ribosomal structure and biogenesis
0.72 182 2-oxoglutarate dehydrogenase E1 component, mitochondrial Energy production and conversion
0.72 4000 Prolyl 4-hydroxylase subunit alpha-2 Not Available
0.718 54 Prothrombin Involved in blood clotting cascade
0.718 280 4-aminobutyrate aminotransferase, mitochondrial Amino acid transport and metabolism
0.716 21 Beta-adrenergic receptor kinase 2 Involved in G-protein coupled receptor kinase activity
0.716 822 Aldose reductase Involved in oxidoreductase activity
0.716 1176 Mitogen-activated protein kinase 1 Involved in MAP kinase activity
0.714 4047 Diacylglycerol kinase gamma Lipid transport and metabolism
0.712 210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase Translation, ribosomal structure and biogenesis
0.712 803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial Energy production and conversion
0.712 3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 Not Available
0.71 90 Tryptophan 5-hydroxylase 2 Amino acid transport and metabolism
0.71 997 Protein kinase C beta type Involved in protein serine/threonine kinase activity
0.71 4066 Protein-arginine deiminase type-1 Not Available
0.708 261 Threonyl-tRNA synthetase, cytoplasmic Translation, ribosomal structure and biogenesis
0.708 508 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Involved in nucleic acid binding
0.708 2180 3-phosphoinositide-dependent protein kinase 1 Involved in protein kinase activity
0.706 209 Aspartoacylase Amino acid transport and metabolism
0.706 934 Proto-oncogene tyrosine-protein kinase Fyn Involved in protein kinase activity
0.704 388 AMP deaminase 1 Involved in deaminase activity
0.704 1064 DNA (cytosine-5)-methyltransferase 1 Replication, recombination and repair
0.704 1970 Protein kinase C alpha type Involved in protein serine/threonine kinase activity
0.704 6288 Low molecular weight phosphotyrosine protein phosphatase Signal transduction mechanisms
0.702 67 Prolyl 4-hydroxylase subunit alpha-1 Involved in oxidoreductase activity
0.702 774 Cysteinyl-tRNA synthetase, cytoplasmic Translation, ribosomal structure and biogenesis
0.702 1596 Protein-glutamine gamma-glutamyltransferase 2 Involved in protein-glutamine gamma-glutamyltransferase activity
0.702 3964 Trimethyllysine dioxygenase, mitochondrial Secondary metabolites biosynthesis, transport and catabolism
0.702 6621 Methionine aminopeptidase 1 Translation, ribosomal structure and biogenesis
0.7 2592 Beta-galactosidase Carbohydrate transport and metabolism
0.7 3448 Thromboxane-A synthase Secondary metabolites biosynthesis, transport and catabolism
0.7 3924 Phospholipase D1 Lipid transport and metabolism
0.7 4042 Glutathione transferase omega-2 Posttranslational modification, protein turnover, chaperones